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EC number: 619-547-7 | CAS number: 211515-46-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- Study performed according to: - Commission Directive 92/69/EEC, Method C.4-D of July31, 1992: Manometric Respirometry Test (EEC Publication No. L 383 A, December 1992) - OECD Guideline for Testing of Chemicals No. 301 F: "Ready Biodegradability: Manometric Respirometry Test", adopted July 17, 1992
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 007
- Report date:
- 2007
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Version / remarks:
- and EU Method C.4-D (Determination of the "Ready" Biodegradability - Manometric Respirometry Test)
- Deviations:
- yes
- Remarks:
- Washing of activated sludge three times instead of twice. No effect presumed as washing should be at least twice and additional washing does not affect the activated sludge.
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- CAT-Acid chloride
- IUPAC Name:
- CAT-Acid chloride
- Details on test material:
- Name: CAT-Acid Chloride
Certificate of Analysis Date: March 30, 2006
Aggregate State at Room Temperature: Liquid
Colour: Brown (according to IBACON personnel)
Molecular Weight: 230.78 g/mol
Molecular Formula: C13H23C10
Calculated Theoretical Oxygen Demand: 2.496 mg/mg
Stability: In water: the test item is considered to be stable under
test conditions
Expiry Date: July 03, 2007
Storage: In original container, at 2-8 degree C, in the dark
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Duration of test (contact time):
- 28 h
Initial test substance concentration
- Initial conc.:
- ca. 102 mg/L
- Based on:
- other: About 102 mg/L corresponding to an oxygen demand of about 255 mg/L based on ThOD of 2.496 mg oxygen demand per mg test item.
Results and discussion
- Details on results:
- Under the test conditions no biodegradation of CAT-acid chloride was
observed within 28 days of incubation. According to the test guidelines,
the test item is considered not to be readily biodegradable.
Any other information on results incl. tables
Biodegradation of Test Item:
Under the test conditions no biodegradation of CAT-acid chloride was
observed within 28 days of incubation. According to the test guidelines,
the test item is considered not to be readily biodegradable.
Biodegradation of Sodium Benzoate:
The reference item sodium benzoate was sufficiently degraded to 63%
after 4 days, and reached a plateau higher than 100% after 11 days of incubation,
thus confirming the suitability of the used activated sludge inoculum.
Biodegradation of the Toxicity Control:
Inthe toxicity control containing both, the test item and the reference item
sodium benzoate, a mean of 36% biodegradation was noted within 11 days
and was at a plateau at 37% to 39% degradation within end of the experiment.
Since the degradation rate was higher than 25% after 14 days, the
test item can be assumed to be not inhibitory on the activated sludge micro
organisms.
Primary Degradation, Hydrolysis and Photolysis of Test Item:
The test item was found to be not stable in aqueous test solutions. Therefore,
no test item analysis could be done.
Adsorption of Test Item to Activated Sludge:
Due to the instability of the test item, the adsorption to activated sludge
could not be determined under the test conditions.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- The test item CAT-acid chloride is not readily biodegradable within the 10
day window or after 28 days of incubation. The test item is not stable under
test conditions. - Executive summary:
Title:
Ready Biodegradability of CAT-Acid Chloride in a Manometric Respirometry Test
Guidelines:
- Commission Directive 92/69/EEC, Method C.4-D of July31, 1992:
Manometric Respirometry Test (EEC Publication No. L 383 A, December
1992)
- OECD Guideline for Testing of Chemicals No. 301 F: "Ready Biodegradability:
Manometric Respirometry Test", adopted July 17, 1992
Material and Methods:
Test Item:
CAT-Acid Chloride
Test Species:
Activated sludge (micro organisms from a domestic waste water treatment
plant) was supplied by the sewage plant Rossdorf, Germany.
Test Design:
The test item CAT-acid chloride was investigated for its ready biodegradability
in a manometric respirometry test over a period of 28 days. The
biodegradation was followed by the oxygen uptake of the microorganisms
during exposure. As a reference item sodium benzoate was
tested simultaneously under the same conditions as the test item, and functioned
as a procedure control.
In addition the primary degradation, hydrolysis and photolysis were followed
by test item specific analysis after 24 hours, 120 hours and 28 days.
The adsorption of CAT-acid chloride to activated sludge was determined
by comparison of test item concentration, dissolved organic carbon (DOC)
and oxygen consumption (BOD) in the treatments after 24 hours and 28
days.
Endpoints :
Degradation rate of test item calculated by the oxygen consumption of the
activated sludge microorganisms after 28 days of incubation.
Reference Item:
Sodium benzoate
Test Concentration:
About 102 mg/L corresponding to an oxygen demand of about 255 mg/L
based on ThOD of 2.496 mg oxygen demand per mg test item.
Test Conditions:
22 degree C, darkness
Results:
Biodegradation of Test Item:
Under the test conditions no biodegradation of CAT-acid chloride was
observed within 28 days of incubation. According to the test guidelines,
the test item is considered not to be readily biodegradable.
Biodegradation of Sodium Benzoate:
The reference item sodium benzoate was sufficiently degraded to 63%
after 4 days, and reached a plateau higher than 100% after 11 days of incubation,
thus confirming the suitability of the used activated sludge inoculum.
Biodegradation of the Toxicity Control:
In the toxicity control containing both, the test item and the reference item
sodium benzoate, a mean of 36% biodegradation was noted within 11 days
and was at a plateau at 37% to 39% degradation within end of the experiment.
Since the degradation rate was higher than 25% after 14 days, the
test item can be assumed to be not inhibitory on the activated sludge micro
organisms.
Primary Degradation, Hydrolysis and Photolysis of Test Item:
The test item was found to be not stable in aqueous test solutions. Therefore,
no test item analysis could be done.
Adsorption of Test Item to Activated Sludge:
Due to the instability of the test item, the adsorption to activated sludge
could not be determined under the test conditions.
Conclusion:
The test item CAT-acid chloride is not readily biodegradable within the 10
day window or after 28 days of incubation. The test item is not stable under
test conditions.
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