Registration Dossier
Registration Dossier
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EC number: 208-914-3 | CAS number: 546-89-4
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 6.29 mg/L
- Assessment factor:
- 1
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 0.945 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.629 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 218.22 mg/L
- Assessment factor:
- 1
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 29.94 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 2.99 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 2.3 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
PNEC sediment (freshwater):
K_(susp-water) = 1.19
RHO_(susp) = 1150
Conversion factor (wwt -> dwt): 4.6
PNEC aqua (freshwater) = 6.29 mg/L
PNEC sediment (freshwater) = (K_(susp-water)/RHO_(susp)) * PNEC aqua
(freshwater) * 1000
= (1.19/1150) * 6.29 * 1000
= 6.51 mg/kg ww
= 29.94 mg/kg dw
The PNEC sediment (freshwater) of dry weight (dw) of lithium acetate is
29.94 mg/kg corresponding to the wet weight (ww) value of 6.51 mg/kg
(conversion factor: 4.6).
PNEC sediment (marine water):
K_(susp-water) = 1.19
RHO_(susp) = 1150
Conversion factor (wwt -> dwt): 4.6
PNEC_aqua (marine water) = 0.629 mg/L
PNEC sediment (marine water) = (K_(susp-water)/RHO_(susp)) * PNEC_aqua
(marine water) * 1000
= (1.19/1150) * 0.629 * 1000
= 0.65 mg/kg ww
= 2.99 mg/kg dw
The PNEC sediment (marine water) of dry weight (dw) of lithium acetate
is 2.99 mg/kg corresponding to the wet weight (ww) value of 0.65 mg/kg
(conversion factor: 4.6).
PNEC soil:
K_(soil-water) = 0.55
RHO_(soil) = 1700
Conversion factor (wwt -> dwt): 1.13
PNEC soil = (K_(soil-water)/RHO_(soil)) * PNEC aqua (freshwater) * 1000
= (0.55/1700) * 6.29 * 1000
= 2.04 mg/kg ww
= 2.30 mg/kg dw
The PNEC (soil) of dry weight (dw) of lithium acetate is 2.3 mg/kg corresponding to a wet weight (ww) value of 2.04 mg/kg (conversion factor: 1.13).
Conclusion on classification
Classification for lithium acetate anhydrous:
Based on the available data, lithium acetate anhydrous and its dihydrate do not have to be classified according to Regulation (EC) No 1272/2008 criteria as the chronic toxicity NOECs are > 1 mg/L and lithium acetate has no potential to bioaccumulate.
Overview of results used fir Classification and Labelling:
Lithium acetate anhydrous:
Fish (Danio rerio), short-term, freshwater: LC50 = 171.42 mg/L
Fish (Danio rerio), long-term, freshwater: NOEC = 27.29 mg/L
Daphnia magna, short-term, freshwater: EC50 = 52.63 mg/L without pH-adjustment; 94.51 mg/L with pH-adjustment
Daphnia magna, long-term, freshwater: NOEC = 6.29 mg/L
Algae (Pseudokirchneriella subcapitata), long-term, freshwater: ErC = 241.31 mg/L and NOEC = 15.73 mg/L
Lithium acetate dihydrate:
Fish (Danio rerio), short-term, freshwater: LC50 = 264.99 mg/L
Fish (Danio rerio), long-term, freshwater: NOEC = 42.18 mg/L
Daphnia magna, short-term, freshwater: EC = 81.35 mg/L without pH-adjustment, 146.09 mg/L with pH-adjustment
Daphnia magna, long-term, freshwater: NOEC = 9.72 mg/L
Algae (Pseudokirchneriella subcapitata), long-term, freshwater: ErC = 373.03 mg/L and NOEC = 24.31 mg/L
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