Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 500-239-5 | CAS number: 68937-90-6
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
No toxicological effects on microorganisms are expected up to the water solubility limit.
Key value for chemical safety assessment
Additional information
One study investigating the biodegradation of Fatty acids, C18-unsaturated, trimers (CAS No. 68937-90-6) is available. The CO2 evolution test followed OECD guideline 301B using domestic activated sludge as inoculum. This test also contained of a toxicity control. The toxicity control replicates each contained 1911 mL of mineral medium, 20 mL of microbial inoculum, the appropriate weight of test item and 69 mL reference material (sodium benzoate). This corresponds to 20 mg DOC/L for the test item and 20 mg DOC/L for sodium benzoate. Thus, the absolute amount of DOC in the toxicity control vessels with 2 L capacity amounts to 80 mg DOC/L.
With 3.67 being the conversion factor (44/12) for carbon to carbon dioxide, the % degradation can be calculated with the following formula: % degradation = (mg CO2 produced) x 100/(mg TOC added x 3.67). Based on this, the toxicity control attained 31.1 % degradation after 28 days of incubation. Thus, in accordance with the OECD Guideline the test substance can be assumed to be non-inhibitory to microbial organisms.
This result is supported by a study investigating the toxicity to microorganisms of Fatty acids, C18-unsaturated, dimers (CAS No. 61788-89-4), a structurally similar substance, which was used as read across in accordance with Regulation (EC) No. 1907/2006, Annex XI, 1.5. grouping of substance and read across approach. The growth inhibition of Pseudomonas putida was recorded in a GLP study equivalent to ISO 10712 (Sewell, 1997). Fatty acids, C18-unsaturated, dimers (CAS No. 61788-89-4) showed no effect on the growth of P. putida at the tested WAF loading rates after 16 hours (EL10/ EL50 > 10000 mg/L, NOELR ≥ 10000 mg/L). Thus it can be concluded that there are no effects up to 10000 mg/L (nominal).
In summary, no toxicity to microorganisms is expected up to 10000 mg/L (nominal) for Fatty acids, C18-unsaturated, trimers (CAS No. 68937-90-6).Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
