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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 701-390-1 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
P: The substance is not considered to be persistent
B: The Log octanol-water partition coefficient of the substance is -0.3 at 25.6 °C and pH 6 using the slow-stirring method (OECD 123). A BCF is calculated of 3.162 L/kg ww for the alkyl-dipropylene triamines and tripropylene tetramines assuming no metabolism. In vitro biotransformation by rainbow trout hepatic subcellulair fraction has been observed for primary alkyl amines and alkyl propane-1,3 -diamines. It is therefore likely that also alkyl dipropylene triamines and alkyl tripropylene tetramines are biotransformed. The calculated BCF indicates a low bioaccumulation potential.
T: The most sensitive species is daphnia magnafor which an EC10 of 712 µg/L has been derived from a 21 d study for tetramine C16-18 (CAS no 1219458-11-3). The study has been performed in natural surface water with a low DOC and suspended matter content. To compensate for possible mitigation by the surface water constituents the EC10 is divided by a factor of 10. As a worst-case it is thus assumed that 90% of the test substance was sorbed. Based on the Kpsusp of 100000 L/kg and a concentration of 15 mg/L suspended matter in surface waters, an adsorbed fraction of 43% is calculated
Based on the available ecotoxicity data it is concluded that the T criterion is not fulfilled for the tetramine C16-18, C18 unsaturated however based on the classification R48 the substance is to be classified as toxic.
- Likely routes of exposure:
The substance has a low vapour pressure, low water solubility and is cationic under environmental conditions and due to that sorbs strongly to soil, sediment and sludge.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.