Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP study according to OECD / EU guidelines

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2006

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 402 (Acute Dermal Toxicity)
GLP compliance:
yes (incl. QA statement)
Limit test:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
1-chloro-3-(4-chlorophenoxy) benzene
EC Number:
614-477-3
Cas Number:
6842-62-2
Molecular formula:
C12 H8 Cl2 O
IUPAC Name:
1-chloro-3-(4-chlorophenoxy) benzene

Test animals

Species:
rat
Strain:
Sprague-Dawley
Sex:
male/female

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Based on:
test mat.

Applicant's summary and conclusion

Conclusions:
In a study according to OECD Guideline No. 402 the LD50 of 3,4’-Dichlordiphenylether was determined to be greater than 2000 mg/kg body weight.