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EC number: 232-489-3 | CAS number: 8052-41-3 A colorless, refined petroleum distillate that is free from rancid or objectionable odors and that boils in a range of approximately 148.8°C to 204.4°C (300°F to 400°F).
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- QSAR prediction:(Q)SAR calculated endpoint
- Qualifier:
- according to guideline
- Guideline:
- other: QSAR
- Principles of method if other than guideline:
- EPI Suite v 4.0/ECOSARv1.00
- GLP compliance:
- no
- Remarks:
- not applicable to QSAR models
- Analytical monitoring:
- not required
- Vehicle:
- not specified
- Test organisms (species):
- other: Daphnid species
- Details on test organisms:
- no further information
- Test type:
- other: QSAR model
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 30 d
- Hardness:
- not applicable. QSAR model
- Test temperature:
- not applicable. QSAR model
- pH:
- not applicable. QSAR model
- Dissolved oxygen:
- not applicable. QSAR model
- Salinity:
- not applicable. QSAR model
- Details on test conditions:
- SMILES : CCCCCCCCCC
CHEM : Stoddard solvent
CAS Num: 8052-41-3
MOL FOR: C10 H22
MOL WT : 142.29
Log Kow: 5.252 (EPISuite Kowwin v1.68 Estimate)
Log Kow: 5.01 (PhysProp DB exp value - for comparison only)
Melt Pt: -29.70 (deg C, PhysProp DB exp value for Wat Sol est)
Wat Sol: 1.409 (mg/L, EPISuite WSKowwin v1.43 Estimate)
Wat Sol: 0.052 (mg/L, PhysProp DB exp value) - Reference substance (positive control):
- no
- Duration:
- 30 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.024 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: (Q)SAR prediction
- Remarks on result:
- other: toxic as determined by (Q)SAR. Chemical may not be soluble enough to measure this predicted effect
- Details on results:
- Daphnid, 30-day,NOEC for freshwater species cited as ChV (chronic value) = 0.024 mg/L (ppm).A NOEC value of 0.024 mg/L has been calculated for the effects of the test substance on the mortality of the Daphnid. This result signifies that the test substance is expected to be toxic.
The model indicated that Stoddard solvent possess properties indicating a potential hazard for the environment based on nominal loadings. - Validity criteria fulfilled:
- yes
- Remarks:
- US EPA accepted QSAR method for chemicals properties assessment.
- Conclusions:
- Daphnid, 30-day,NOEC for freshwater species cited as ChV (chronic value) = 0.024 mg/L (ppm).A NOEC value of 0.024 mg/L has been calculated for the effects of the test substance on the mortality of the Daphnid. This result signifies that the test substance is expected to be toxic.
The model indicated that Stoddard solvent possess properties indicating a potential hazard for the environment based on nominal loadings. - Executive summary:
ECOSAR QSAR model predicts that NOEC for fresh water species Daphnid cited as ChV (chronic value) would to be 0.024 mg/l.
This result signifies that the test substance is expected to be toxic.
The model indicated that Stoddard solvent possess properties indicating a potential hazard for the environment based on nominal loadings.
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 21 Days
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Published data in readily available literature considered as a reliable data source.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 211 (Daphnia magna Reproduction Test)
- GLP compliance:
- not specified
- Analytical monitoring:
- yes
- Details on sampling:
- Duplicate samples of freshly prepared WAFs and composited replicate old test solutions were collected each day.
- Vehicle:
- yes
- Details on test solutions:
- Daphnia magna, were exposed for 21 days to five nominal loading levels and a control following OECD TG 211. Individual WAFs were prepared for each loading level, and the study was conducted with periodic renewal of the test solutions.
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Daphnids used in the test were from laboratory in-house culture. Daphnids were =24 hrs old at the start of the test. Daphnids were fed 0.2 ml of algal suspension (Ankistrodesmus falcatus, 4 x 107 cells/ml) and 0.05 ml of a yeast, cereal leaves and digested flaked fish food (YCT) suspension daily during the test.
- Test type:
- semi-static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 21 d
- Hardness:
- The water used in this study had a total hardness range of 170-180 mg/l as CaCO3, total alkalinity of 120-130 mg/l as CaCO3
- Test temperature:
- Water temperature was 19 to 21° C
- pH:
- 7.5 to 8.5
- Dissolved oxygen:
- Dissolved oxygen concentrations were 9.1 to 9.2 in the new solutions and 8.7 to 9.4 in the old solutions.
- Salinity:
- Not applicable
- Nominal and measured concentrations:
- nominal loading levels :1.62,1.4, 1.19, 0.43, 0.37,0.33, 0.28, 0.10
- Reference substance (positive control):
- not specified
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.1 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
- Duration:
- 21 d
- Dose descriptor:
- NOELR
- Effect conc.:
- 0.28 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
- Duration:
- 21 d
- Dose descriptor:
- EL50
- Effect conc.:
- 1.19 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
- Duration:
- 21 d
- Dose descriptor:
- EC50
- Effect conc.:
- 0.33 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
- Details on results:
- The daphnid 21-day EL50 value for reproduction was 1.19 mg/L (based on nominal loading levels), while the measured EC50 value was 0.33 mg/L. The NOELR value for reproduction from this study was 0.28 mg/L, while the NOEC value for reproduction was 0.10 mg/L
- Validity criteria fulfilled:
- yes
- Conclusions:
- The daphnid 21-day EL50 value for reproduction was 1.19 mg/L (based on nominal loading levels), while the measured EC50 value was 0.33 mg/L. The NOELR value for reproduction from this study was 0.28 mg/L, while the NOEC value for reproduction was 0.10 mg/L
- Executive summary:
Daphnia magna, were exposed for 21 days to five nominal loading levels and a control following OECD TG 211. Individual WAFs were prepared for each loading level, and the study was conducted with periodic renewal of the test solutions.
The daphnid 21-day EL50value for reproduction was 1.19 mg/L (based on nominal loading levels), while the measured EC50value was 0.33 mg/L. The NOELR value for reproduction from this study was 0.28 mg/L, while the NOEC value for reproduction was 0.10 mg/L.
Referenceopen allclose all
Overview of QSARs estimations on long-term aquatic toxicity of Stoddard solvent to Daphnid
Method
|
Results |
Remarks |
Reference |
QSAR estimate |
Daphnid, 30-day, ChV (chronic value) = 0.024 mg/L (ppm)
Daphnid , 48-hr LC50 = 0.107 mg/L (ppm)
|
Reliable with restrictions, QSAR estimated data |
ECOSAR Program (v1.00) |
ECOSAR QSAR model predicts that NOEC for fresh water species Daphnid cited as ChV (chronic value) would to be 0.024 mg/l.
This result signifies that the test substance is expected to be toxic.
Daphnid, 30-day, ChV (chronic value) = 0.024 mg/L (ppm)
Daphnid , 48-hr LC50 = 0.107 mg/L (ppm)
Description of key information
ECOSAR QSAR model predicts that NOEC for fresh water species Daphnid cited as ChV (chronic value) would to be 0.024 mg/l.
The daphnid 21-day EL50 value for reproduction was 1.19 mg/L (based on nominal loading levels), while the measured EC50 value was 0.33 mg/L. The NOELR value for reproduction from this study was 0.28 mg/L, while the NOEC value for reproduction was 0.10 mg/L
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.28 mg/L
Marine water invertebrates
Marine water invertebrates
- Effect concentration:
- 0.028 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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