N-hydroxyphthalimide

Density

Link to relevant study record(s)

Reference

Endpoint:

density

Remarks:

density

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2017-03-10 – 2017-03-14

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

Experimental result performed using standard methods of analysis

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Principles of method if other than guideline:

The density is calculated from the difference in weight between the full and empty pycnometer and its volume

GLP compliance:

no

Type of method:

pycnometer method

Specific details on test material used for the study:

- Name of test material:2-hydroxy-1H-isoindole-1,3(2H)-dione
- Molecular formula: C8H5NO3
- Molecular weight: 163.132 g/mol
- Smiles notation: c12c(C(=O)N(C1=O)O)cccc2
- Substance type: Organic
- Physical state: Solid

Type:

density

Density:

1.616 g/cm³

Temp.:

20 °C

Method Details		Observations		Remarks if, any
Guideline	OECD 109	1^stReading	2^nd Reading
Method	Adapted from ASTM 854-02
Principle of method	The density of test item is determined by using pyknometer. It is the ratio of mass of the unit volume of test item at a stated temperature to mass of the same volume of gas free distilled water at a stated temperature.
Test temperature (°C)	-	20^oC	20^oC
Atmospheric pressure (in hPa)	-	976.2	977.8
Weight of empty dry pyknometer (Wp)		29.229	30.726
Weight of pyknometer filled with water (WA)		79.918	80.704
Weight of pyknometer + test Item (WPS)		35.051	35.918
Weight of pyknometer +test Item+ water (WB)		82.163	82.672

 

 

CALCULATIONS:

	Calculated values
	1^stCalculation	2^nd Calculation
Wo=WPS-WP	5.8220	5.1920
(WA-WB)	-2.2450	-1.9680
Specific gravity = WO/[WO+ (WA-WB)]	1.6276	1.6104
Specific Gravity; Gs	1.6276	1.6104
Density (g/cm³)	1.6246	1.6075
Mean Density (g/cm³)	1.6161

Conclusions:

The density of test item 2-hydroxy-1H-isoindole-1,3(2H)-dione (CAS No. 524-38-9)was determined following OECD Guideline 109 and according to the Adapted from ASTM D854-02 using glass pyknometer.The mean density of 2-hydroxy-1H-isoindole-1,3(2H)-dione was determined to be 1.616 g/cm³ at 20°C and 977.0 hPa.

Executive summary:

The density of test item 2-hydroxy-1H-isoindole-1,3(2H)-dione (CAS No. 524-38-9)was determined following OECD Guideline 109 and according to the Adapted from ASTM D854-02 using glass pyknometer.The mean density of 2-hydroxy-1H-isoindole-1,3(2H)-dione was determined to be 1.616 g/cm³ at 20°C and 977.0 hPa.

Description of key information

The density of test item 2-hydroxy-1H-isoindole-1,3(2H)-dione (CAS No. 524-38-9)was determined following OECD Guideline 109 and according to the Adapted from ASTM D854-02 using glass pyknometer.The mean density of 2-hydroxy-1H-isoindole-1,3(2H)-dione was determined to be 1.616 g/cm³ at 20°C and 977.0 hPa.

Key value for chemical safety assessment

Relative density at 20C:

1.616

Additional information

The density of test item 2-hydroxy-1H-isoindole-1,3(2H)-dione (CAS No. 524-38-9)was determined following OECD Guideline 109 and according to the Adapted from ASTM D854-02 using glass pyknometer.The mean density of 2-hydroxy-1H-isoindole-1,3(2H)-dione was determined to be 1.616 g/cm³ at 20°C and 977.0 hPa.

Other supporting studies from various reliable sources such as authoritative database and handbook also indicates that the density of chemical 2-hydroxy-1H-isoindole-1,3(2H)-dione was determined to be in the range of 1.58 g/cm3 to 1.601 g/cm3

As the data from lab has K1 reliability and the test was performed using OECD guidelines which has the value of density as 1.616 g/cm3 at 20 degree C, thus considered as key study for the chemical safety assessment.