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Diss Factsheets
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EC number: 944-042-6 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: inherent biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From July 17, 2000 to March 16, 2001
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 302 B (Inherent biodegradability: Zahn-Wellens/EMPA Test)
- GLP compliance:
- no
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, adapted
- Details on inoculum:
- Concentration of sludge: 1 g dry matter
- Duration of test (contact time):
- ca. 28 d
- Initial conc.:
- ca. 150 mg/L
- Based on:
- other: TOC
- Parameter followed for biodegradation estimation:
- TOC removal
- Details on study design:
- TEST CONDITIONS
- Test vessel: conical Erlenmeyer flask 5 l.
- Composition of medium:
— Solution 1: KH2PO4 8,5 g/L H2O
K2HPO4 21.75 g/L H2O
Na2HPO4 2H2O 33.4 g/L H2O
NH4Cl 0.5 g/L H2O
— Solution 2: CaCl 2 2H2O 36.4 g/L H2O
— Solution 3: MgSO4 7H2O 22.5 g/L H2O
— Solution 4: FeCl 3 6H2O 0.25 g/L H2O
Add 1000 mL of deionized water:
— Solution 1: 10 mL
— Solution 2: 1 mL
— Solution 3: 1 mL
— Solution 4: 1 mL
- Test temperature: 22 ± 2 ºC
- pH: 8
- pH adjusted: yes from 6.5 to 8
- Continuous darkness: no, diffused light.
TEST SYSTEM
- Number of culture flasks/concentration: 2
- Method used to create aerobic conditions: continuous aeration. - Reference substance:
- diethylene glycol
- Parameter:
- % degradation (TOC removal)
- Value:
- < 1
- Sampling time:
- 28 d
- Results with reference substance:
- 100% within 19 days of test period.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- other: not readily nor inherently biodegradable
- Conclusions:
- The substance is not biodegradable within 28 days of test period.
- Executive summary:
The substance has been tested for inherent biodegradation according to the OECD guideline 302B (1992) and Royal Decree 363/1995 (BOE no.133 of June 1995).
Biodegradation is defined as the decomposition of an organic compound by biological action of microorganisms, resulting in the disappearance of the original molecular structure and the formation of small organic molecules. The results are expressed as percentage of biodegradation at 28 days. The result obtained in this test indicates that there is not biodegradation within 28 days of test period, i.e. <1 %, based on TOC removal.
Reference
800 ml of mineral medium are introduced into 5 liter Erlenmeyer flask and added sufficient volumes of mother solutions of the substance (or reference) and inoculum to two separate flasks to obtain a substance concentration based on TOC equivalent to 150 mg/l and a concentration of 1 g of dry material/l .
Add the required volume of mineral medium to reach the test volume (2 l). Taken into account that 1.041 g/l of product (0.94 g/l of active substance) presents a TOC value of 143.9 mg/l, a solution of the product of 1085 mg/l it is performed (1953 mg/l of active ingredient) to obtain a value of 150 mg TOC/l.
Description of key information
not readily biodegradable
Key value for chemical safety assessment
- Biodegradation in water:
- not biodegradable
Additional information
No data is available about the ready biodegradability. The only data available is about the inherent biodegradation. The substance has been tested according to the guideline OECD 302B. After 28 days of test period the biodegradation recorded was less than 1%. It was confirmed that the substance is neither readily, neither inherently biodegradable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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