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Diss Factsheets
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EC number: 279-365-5 | CAS number: 80010-51-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
- Category name:
- 7.4.1 – EC 279-365-5 – Acid Blue 225 & EC 267-224-0 – Acid Blue 260 - Category
Justifications and discussions
- Category definition:
- See section “1. HYPOTHESIS FOR THE CATEGORY APPROACH” of the attached report: “7.4.1 - EC 279-365-5 & EC 267-224-0 - Acid Blue 225 & Acid Blue 260 – Reasoning.pdf”.
- Category description:
- 2. CATEGORY JUSTIFICATION:
See section “3. CATEGORY APPROACH JUSTIFICATION” of the attached report: “7.4.1 - EC 279-365-5 & EC 267-224-0 - Acid Blue 225 & Acid Blue 260 – Reasoning”. - Category rationale:
- 3. APPLICABILITY DOMAIN OF THE CATEGORY:
The choice of the target and the potential source substances that compose the category was based on a clustering method described in “7.4.1 - EC 279-365-5 & EC 267-224-0 - Acid Blue 225 & Acid Blue 260 - ClusteringMethod.pdf”. This method allows to calculate the similarity of each potential source with the targets and the similarity among the targets. The comparison between two molecules is based on the Tanimoto Coefficient that compares the Daylight fingerprints (as calculated in Python by RDKit) of the two molecules.
In this case, among the pool of potential sources (the ones with a reliable value for the endpoint of interest) the sources Orasol Blau 761B (EC 414-110-5) and Reactive Blue FC 60866 (EC 414-040-5) were selected based on their similarity with the targets [Similarity Indexes range from 0.777 to 0.893] and the quality of the available data.
Moreover, a table containing the comparison between the physicochemical properties of targets and sources is reported in section “4. DATA MATRIX” of the attached report: “7.4.1 - EC 279-365-5 & EC 267-224-0 - Acid Blue 225 & Acid Blue 260 – Reasoning.pdf”.
The target and the source substances can be considered in the applicability domain of the category due to their high structural similarity [Similarity Index ≥ 0.777] and their similar physicochemical properties [see section “4. DATA MATRIX” of the attached report: “7.4.1 - EC 279-365-5 & EC 267-224-0 - Acid Blue 225 & Acid Blue 260 – Reasoning.pdf”].
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.