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EC number: 277-040-2 | CAS number: 72927-99-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Auto flammability
Administrative data
Link to relevant study record(s)
- Endpoint:
- relative self-ignition temperature (solids)
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Justification for type of information:
- REPORTING FORMAT FOR THE ANALOGUE APPROACH
1. HYPOTHESIS FOR THE ANALOGUE APPROACH
This read-across is based on the hypothesis that the source and the target substance have very similar physicochemical and (eco)toxicological properties because their chemical structures are nearly identical. An analogue approach has thus been employed. The target substance is the meta-isomer of the dye Reactive Blue 049, where the sulphonate group is bound at the meta-position of the aminobenzene moiety. The source chemical is the reaction mass of both the meta-isomer and the para-isomer of Reactive Blue 049.
The presence of sulphonate groups make both dyes highly water soluble and therefore less critical for human health and environmental issues. Based on their chemical similarity, similar properties are expected in both humans and the environment.
2. SOURCE AND TARGET CHEMICAL(S)
Source: Reactive Blue 49 meta/para (CAS# 72214-18-7 / EC# 276-481-8)
Target: Reactive Blue 49 meta (CAS# 72927-99-2 / EC# 277-040-2)
3. ANALOGUE APPROACH JUSTIFICATION
see attachment under 4.2 Melting point / freezing point - Reason / purpose for cross-reference:
- read-across source
- Relative self-ignition temperature:
- > 550 °C
- Remarks on result:
- no self ignition observed under the test conditions
- Conclusions:
- The auto-ignition temperature of the test item is >550 °C
- Executive summary:
The determination of the autoignition temperature of the test item was performed in accordance with the EEC Directive Annex V of 67/548 Test A 16 Auto- ignition temperature for solids. No autoignition took place up to 550 °C.
- Endpoint:
- relative self-ignition temperature (solids)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2014
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.15 (Auto-Ignition Temperature (Liquids and Gases))
- Version / remarks:
- Although the test substance is a solid, the method for liquids was used, as it was available at laboratory. For this purpose the dye was suspended/dissolved in a small amount of water and injected into the machine. There the water was evaporated and the auto-ignition temperature of the solid was measured.
- GLP compliance:
- no
- Relative self-ignition temperature:
- > 550 °C
- Remarks on result:
- no self ignition observed under the test conditions
- Conclusions:
- The auto-ignition temperature of the test item is >550 °C
- Executive summary:
The determination of the auto-ignition temperature of the test item was performed in accordance with the EEC Directive Annex V of 67/548 Test A 15 Auto-ignition temperature (Liquids and Gases). The method determines the minimum temperature of the inner surface of an enclosure that will result in ignition of a gas, vapour or liquid injected into the enclosure. Although the test substance is a solid, the method for liquids was used, as it was available at laboratory. For this purpose the dye was suspended/dissolved in a small amount of water and injected into the machine. There the water was evaporated and the auto-ignition temperature of the solid was measured.
The measurement took place in an apparatus for determination of auto-ignition temperature according to DIN 51794. The temperature of the oven and the sample were continuously recorded while the temperature of the oven was increased to approximately 550 °C at a rate of about 3- 5 °C/min. Then the test item was added drop by drop with a pipette through the cylinder hole into the Erlenmeyer flask. The auto-ignition temperature, as obtained by this method, is the minimum ambient temperature expressed in °C at which a certain volume of a substance ignites under defined conditions.
According to this test method, no auto-ignition took place up to 550 °C.
Referenceopen allclose all
Description of key information
The auto-ignition temperature is higher than 550 °C
Key value for chemical safety assessment
- Autoflammability / Self-ignition temperature at 101 325 Pa:
- 550 °C
Additional information
The determination of the auto-ignition temperature of the source substance was performed in accordance with the EEC Directive Annex V of 67/548 Test A 15 Auto-ignition temperature (Liquids and Gases). The method determines the minimum temperature of the inner surface of an enclosure that will result in ignition of a gas, vapour or liquid injected into the enclosure. Although the test substance is a solid, the method for liquids was used, as it was available at the laboratory. For this purpose the dye was suspended/dissolved in a small amount of water and injected into the machine, where the water evaporated and the auto-ignition temperature of the solid was measured.
According to this test method, no auto-ignition took place up to 550 °C. The structurally related target substance will show similar results, and will not show auto-ignition up to 550°C.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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