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Diss Factsheets
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EC number: 248-777-7 | CAS number: 28015-99-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- December 18, 1980 - January 1, 1981
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: limited report, non GLP, exposure concentrations not clear. The information in the report is limited to the information in the summary.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 981
- Report date:
- 1981
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: FHSLA, 16 CFR 1500
- GLP compliance:
- no
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- Magnesium bis(dinonylnaphthalenesulphonate)
- EC Number:
- 248-777-7
- EC Name:
- Magnesium bis(dinonylnaphthalenesulphonate)
- Cas Number:
- 28015-99-8
- Molecular formula:
- Mg[C28H43O3S]2
- IUPAC Name:
- magnesium bis(dinonylnaphthalenesulphonate)
- Test material form:
- liquid: viscous
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Sprague-Dawley
- Sex:
- male/female
- Details on test animals or test system and environmental conditions:
- TEST ANIMALS
- Source: Taconic Farms
- Age at study initiation: not reported
- Weight at study initiation: Males: 241-300 g; Females: 201-240 g
- Fasting period before study: NA
- Housing: individually
- Diet: Fi sher Rat Chow ad libitum
- Water: ad libitum
- Acclimation period: 31 days
ENVIRONMENTAL CONDITIONS
- Temperature (°C): not reported
- Humidity (%): not reported
- Air changes (per hr): not reported
- Photoperiod (hrs dark / hrs light): 12/12
Administration / exposure
- Route of administration:
- inhalation
- Type of inhalation exposure:
- not specified
- Vehicle:
- other: oil
- Details on inhalation exposure:
- GENERATION OF TEST ATMOSPHERE / CHAMBER DESCRIPTION: no data
VEHICLE: oil
- Concentration of test material in vehicle: 25% - Analytical verification of test atmosphere concentrations:
- no
- Duration of exposure:
- ca. 4.5 h
- Concentrations:
- 5.1 mg/L (2.6 mg/L as active)
- No. of animals per sex per dose:
- 5 males + 5 females
- Control animals:
- no
- Details on study design:
- - Duration of observation period following administration: 14 days
- Frequency of observations and weighing: not indicated (weight at study start and termination)
- Necropsy of survivors performed: no
- Other examinations performed: clinical signs - Statistics:
- NA
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LC50
- Effect level:
- > 2.6 mg/L air (nominal)
- Based on:
- test mat.
- Exp. duration:
- 4.5 h
- Mortality:
- none
- Clinical signs:
- other: non observed
- Body weight:
- within expected ranges
- Gross pathology:
- not performed
Applicant's summary and conclusion
- Interpretation of results:
- practically nontoxic
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The LC50 of the test substance is > 2.6 mg/L.
- Executive summary:
Rats (5/sex) were exposed to the test substance at 2.6 mg/L by inhalation. No mortality, clinical signs or effects on body weight were observed. It is therefore concluded that the LC50 is >2.6 mg/L
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