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Diss Factsheets
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EC number: 257-768-7 | CAS number: 52236-73-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- other: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Study period:
- 1994
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods with acceptable restrictions
- Remarks:
- Experimental study performed on the non-salified form of the substance under registration. The difference in counter-ion does not impact the study outcomes because the ecotoxicological properties are determined by the base of the substance.
- Qualifier:
- according to guideline
- Guideline:
- ISO 6341 (Water quality - Determination of the Inhibition of the Mobility of Daphnia magna Straus (Cladocera, Crustacea))
- Deviations:
- not specified
- GLP compliance:
- no
- Analytical monitoring:
- no
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM
- Common name: Daphnia Magna.
- Strain: Straus.
- Source: own laboratory breeding.
- Age at study initiation: young daphnia born in 24 hours.
- Method of breeding: aperiodic parthenogenesis. The grow-up gravid females are separated into dilution water.
- Feeding during test: no.
ACCLIMATION
- Acclimation period: young daphnia born in 24 hours are segregated to the handling container from which they entered the experiment. - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
- Test temperature:
- 20 ± 2 °C
- pH:
- 7.8 ± 0.2
- Dissolved oxygen:
- > 7 mg/l
- Nominal and measured concentrations:
- Nominal: 100, 800, 700, 600, 500, 400, 200, 100, 60 mg/l
- Details on test conditions:
- TEST SYSTEM
- Biomass loading rate: 5 Daphnia in 10 ml solution.
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: the dilution water was prepared just before the test by admixing 25 ml of stored solutions A, B, C and D into 1 000 ml of distilled water.
A. 11.76 g CaCl2.2H2O in 1 litre of distilled water.
B. 4.93 g MgSO4.7H2O in 1 litre of distilled water.
C. 2.59 g NaHCO3 in 1 litre of distilled water.
D. 0.23 g KCl in 1 litre of distilled water.
- Hardness: CaCO3 250 ± 25 mg/l.
- Conductivity:0.1 µS/m
- Ratio Ca:Mg: 4 : 1 - Reference substance (positive control):
- yes
- Remarks:
- the sensitivity of the test species and correctness of test performance is periodically verified in three-month period by testing with the refence substance, potassium dichromate.
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 302 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Details on results:
- EC50 (24h): 608 mg/l (nominal)
- Validity criteria fulfilled:
- yes
- Remarks:
- immobilisation in the controls did not exceed 10 % at the end of the test and the dissolved oxygen concentrations (throughout the test) remained above 2 mg/l
- Conclusions:
- EC50 (48h): 302 mg/l (nominal)
- Executive summary:
Method
The substance was tested on Acute immobilisation test on Daphnia magna, according to ISO 6341 15 (Water quality - Determination of the Inhibition of the Mobility of Daphnia magna Straus (Cladocera, Crustacea)). Daphnids were exposed to the nominal concentration of 100, 800, 700, 600, 500, 400, 200, 100, 60 mg/l, over a period of 48 hours.
Results
EC50 (24h): 608 mg/l (nominal)
EC50 (48h): 302 mg/l (nominal)
Reference
Description of key information
Non harmful/toxic to aquatic invertebrates, short-term exposure
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 302 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.