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Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Principles of method if other than guideline:
Laser light scattering.
The particle size distribution was analyzed using the Mastersizer 2000 tool, which uses the technique of laser diffraction to measures the size of particles. It measures the intensity of light scattered as a laser beam passes through a dispersed particulate sample. This data is then analyzed to calculate the size of the particles that created the scattering pattern.
GLP compliance:
no
Type of method:
Laser scattering/diffraction
Type of distribution:
volumetric distribution
Percentile:
D50
Mean:
59.048 µm
Remarks on result:
other: Migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.
Percentile:
D10
Mean:
16.835 µm
Remarks on result:
other: Analysis carried out after 2 minutes of ultrasonic treatment.
Percentile:
D50
Mean:
59.048 µm
Remarks on result:
other: Analysis carried out after 2 minutes of ultrasonic treatment.
Percentile:
D90
Mean:
115.789 µm
Remarks on result:
other: Analysis carried out after 2 minutes of ultrasonic treatment.
Conclusions:
The particle size distribution was analyzed using laser diffraction. Mass median diameter: D50: 59.048 µm (D10: 16.835 µm, D 90: 115.789 µm)
Executive summary:

The particle size distribution was analyzed using the Mastersizer 2000 tool, which uses the technique of laser diffraction to measures the size of particles. It measures the intensity of light scattered as a laser beam passes through a dispersed particulate sample. This data is then analyzed to calculate the size of the particles that created the scattering pattern.

Analysis carried out after 2 minutes of ultrasonic treatment:

Mass median diameter: D50: 59.048 µm (D10: 16.835 µm, D 90: 115.789 µm)

Description of key information

The particle size distribution was analyzed using laser diffraction. Mass median diameter: D50: 59.048 µm (D10: 16.835 µm, D 90: 115.789 µm)

Additional information

Laser light scattering