Registration Dossier
Registration Dossier
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EC number: 208-523-8 | CAS number: 532-02-5
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Authoritative data base
- Title:
- Danish QSAR study for CAS No.: 532-02-5
- Author:
- Danish (Q)SAR Database
- Year:
- 2 016
- Bibliographic source:
- Database developed by National Food Institute, Technical University of Denmark, with support from the Danish Environmental Protection Agency, the Nordic Council of Ministers and the European Chemicals Agency.
Materials and methods
- Principles of method if other than guideline:
- The prediction is done using Danish (Q)SAR Database
- GLP compliance:
- no
Test material
- Reference substance name:
- Sodium naphthalene-2-sulphonate
- EC Number:
- 208-523-8
- EC Name:
- Sodium naphthalene-2-sulphonate
- Cas Number:
- 532-02-5
- Molecular formula:
- C10H8O3S.Na
- IUPAC Name:
- sodium naphthalene-2-sulphonate
- Details on test material:
- SMILES: c12c(cc(S(=O)(=O)O)cc1)cccc2
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Raphidocelis subcapitata (previous names: Pseudokirchneriella subcapitata, Selenastrum capricornutum)
Study design
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 72 h
Results and discussion
Effect concentrations
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- 4 767.52 mg/L
- Nominal / measured:
- estimated
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
Applicant's summary and conclusion
- Conclusions:
- Based on the QSAR prediction done using the Danish (Q)SAR Database, the 72 hours EC50 was estimated to be 4767.52 mg/L on Microalgae Pseudokirchnerella subcapitata for substance Sodium naphthalene-2-sulphonate with growth inhibition effects. Thus based on this value it can be concluded that the substance can be classified asnoon hazardous as per the criteria of CLP regulation.
- Executive summary:
Based on the QSAR prediction done using the Danish (Q)SAR Database, the 72 hours EC50 was estimated to be 4767.52 mg/L on Microalgae Pseudokirchnerella subcapitata for substance Sodium naphthalene-2-sulphonate with growth inhibition effects. Thus based on this value it can be concluded that the substance can be classified asnoon hazardous as per the criteria of CLP regulation.
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