Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 224-618-7 | CAS number: 4430-18-6
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
After 72 hours of exposure to test item sodium 4-[(9,10-dihydro-4-hydroxy-9,10-dioxo-1-anthryl)amino]toluene-3-sulphonate(CAS No. 4430-18-6)to various nominal test concentrations, EC50 was found to be 79.788 mg/l graphically and through probit analysis.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 79.788 mg/L
Additional information
Experimental data and prediction model based estimation was used to evaluate the algal toxicity of the test compound Acid violet 43. the summary is as below:
The effect of test item sodium 4-[(9,10-dihydro-4-hydroxy-9,10-dioxo-1-anthryl)amino]toluene-3-sulphonate, CAS No. 4430-18-6 was studied on the growth of fresh water green alga Chlorella vulgaris.The study was conducted following OECD guideline 201- Alga, growth inhibition test. The test concentration chosen for the study were 6.25mg/l, 12.5mg/l, 25mg/l, 50mg/l, 100mg/l and 200mg/l. The test concentrations were prepared using stock solution of the test item using mineral media. The green alga was exposed to the test concentration for a period of 72 hours to observe average specific growth rate and % growth inhibition under the effect of the test item. EC50 calculated graphically through probit analysis was observed to be 79.788mg/L.
The median effective concentration (EC50) for the test compound sodium 4 -[(9,10 -dihydro-4 -hydroxy-9,10 -dioxo-1 -anthryl)amino]toluene-3 -sulphonate as predicted by Danish QSAR estimation database in a 96h study using green algae is found to be 25.528 mg/L.
Experimental data suggests that the test chemical does not classify for toxicity to lagae and cyanobacteria.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
