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EC number: 259-915-0 | CAS number: 55947-46-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
96 hrs aquatic toxicity study (SSS QSAR prediction model, 2016) was conducted to assess toxic effects of the test compound2-Propyne-1-sulfonic acid, sodium salt(CAS no 55947-46-1) and the results were predicted. The study was based on the effects of the test compound on the fish in a static fresh water system. The predicted data suggests the lethal concentration (LC50) for the test compound 2-Propyne-1-sulfonic acid, sodium salt was estimated to be 57.029315948 mg/L on the basis of mortality.
But the partition coefficient - Kow for the chemical was -2.16 which is less than criteria i.e 4 and bioaccumulation potential (BCF) also below criteria of 2000 i.e reported bioaccumulation value is 3.16 therefore the chemical was not considered for further classification.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 57.029 mg/L
Additional information
Various studies for the target chemical 2-Propyne-1-sulfonic acid, sodium salt and read across study were reviewed to summarize the following information:
96 hrs aquatic toxicity study (SSS QSAR prediction model, 2016) was conducted to assess toxic effects of the test compound 2-Propyne-1-sulfonic acid, sodium salt and the results were predicted. The study was based on the effects of the test compound on the fish in a static fresh water system. The predicted data suggests the lethal concentration (LC50) for the test compound 2-Propyne-1-sulfonic acid, sodium salt was estimated to be 57.029(CAS no 55947-46-1) 315948 mg/L on the basis of mortality.
But the partition coefficient - Kow for the chemical was -2.16 which is less than criteria i.e 4 therefore the chemical was considered as not classified as per CLP regulations.
Other predicted model for target chemical indicate that the lethal concentration (LC50) for the test compound2-Propyne-1-sulfonic acid, sodium salt was estimated to be 5500000 mg/l.
And read across substance sodium 2–methylprop–2–ene–1–sulphonate (1561-92-8) indicate that the during experiment the toxicity to fish LC0 value determined to be >= 100 mg/l on the basis of mortality effect.( IUCLID dataset; EUROPEAN COMMISSION European Chemicals Bureau,2000)
Same source for other read across Sodium vinylsulfonate (Cas no. 3039-83-6) shows the LC0 value to be > 500 mg/l on the basis of mortality effect.
Thus based on the various predicted and experimental studies the test substance 2-Propyne-1-sulfonic acid, sodium salt (CAS no 55947-46-1) consider to be non toxic to fish.
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