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EC number: 235-227-6 | CAS number: 12136-45-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- other: Published data
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Principles of method if other than guideline:
- Diatoms were cultured in synthetic dilution water under controlled conditions. Tests were made by putting standard inoculum of cells in each of the
150 ml Erlenmeyer flasks, and comparing the number of cells produced at the end of a 5-day period. A graded series of test concentrations were used. - GLP compliance:
- not specified
- Analytical monitoring:
- yes
- Vehicle:
- yes
- Details on test solutions:
- Diatoms were cultured in synthetic dilution water under controlled conditions. Tests were made by putting standard inoculum of cells in each of the
150 ml Erlenmeyer flasks, and comparing the number of cells produced at the end of a 5-day period. A graded series of test concentrations were used. - Test organisms (species):
- Nitscheria linearis
- Details on test organisms:
- Nitscheria linearis (diatom)
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 120 h
- Hardness:
- 10 mg/L CaCO3
- Test temperature:
- 22 °C
- Dissolved oxygen:
- 5 to 9 mg/L
- Duration:
- 120 h
- Dose descriptor:
- EC50
- Effect conc.:
- 1 337 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Details on results:
- Toxicity to aquatic algae and cyanobacteria was determined with Nitscheria linearis (diatom) and was determined as 120h-EC50 = 1337mg/L
- Validity criteria fulfilled:
- not specified
- Conclusions:
- Toxicity to aquatic algae and cyanobacteria was determined with Nitscheria linearis (diatom) and was determined as 120h-EC50 = 1337mg/L
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- QSAR prediction: US EPA accepted QSAR method for chemicals properties assessment.
- Qualifier:
- according to guideline
- Guideline:
- other: QSAR model
- Principles of method if other than guideline:
- ECOSAR Program(v1.00)
- GLP compliance:
- no
- Analytical monitoring:
- no
- Vehicle:
- no
- Test organisms (species):
- other: Green Algae
- Details on test organisms:
- QSAR model-Green Algae
- Test type:
- other: QSAR model
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
- Test temperature:
- not applicable. QSAR model
- pH:
- not applicable. QSAR model
- Dissolved oxygen:
- not applicable. QSAR model
- Salinity:
- not applicable. QSAR model
- Nominal and measured concentrations:
- not applicable. QSAR model
- Details on test conditions:
- -Name of test material (as cited in study report:Potassium oxide
CAS Number: 12136-45-7
SMILES : KOK
CHEM : Potash (potassium oxide)
MOL FOR: O1 K2
MOL WT : 94.20
Values used to Generate ECOSAR Profile
Log Kow: -1.380 (EPISuite Kowwin v1.68 Estimate)
Wat Sol: 1E+006 (mg/L, EPISuite WSKowwin v1.43 Estimate) - Reference substance (positive control):
- no
- Duration:
- 96 h
- Dose descriptor:
- EC50
- Effect conc.:
- 1 368.296 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- not specified
- Basis for effect:
- not specified
- Duration:
- 30 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 178.832 mg/L
- Nominal / measured:
- not specified
- Conc. based on:
- not specified
- Basis for effect:
- not specified
- Remarks on result:
- other: NOEC cited as a ChV value
- Details on results:
- Green Algae, 96-hr EC50 =1368.296 mg/L (ppm)
Green Algae, 30-day, NOEC cited as a ChV value = 178.832 mg/L(ppm) - Validity criteria fulfilled:
- yes
- Remarks:
- method for chemicals properties assessment.
- Conclusions:
- Green Algae, 96-hr EC50 =1368.296 mg/L (ppm)
Green Algae, 30-day, NOEC cited as a ChV value = 178.832 mg/L(ppm) - Executive summary:
The ECOSAR QSAR model predicts that 30-day, NOEC cited as a ChV value would to be 178.832 mg/L (ppm) Green Algae.
The ECOSAR QSAR model predicts that 96-hr EC50 value would to be 1368.296 mg/L (ppm) for Green Algae.
Referenceopen allclose all
Overview of QSARs estimations on aquatic toxicity of Dipotassium oxide/Potassium oxide to Green algae
Method
|
Results |
Remarks |
Reference |
QSAR estimate |
Green Algae, 96-hr EC50 =1368.296 mg/L (ppm) Green Algae, 30-day, NOEC cited as a ChV value = 178.832 mg/L(ppm)
|
Reliable with restrictions, QSAR estimated data |
ECOSAR Program (v1.00) |
Green Algae, 96-hr EC50 =1368.296 mg/L (ppm)
Green Algae, 30-day, NOEC cited as a ChV value = 178.832 mg/L(ppm)
Description of key information
Toxicity to aquatic algae and cyanobacteria was determined with Nitscheria linearis (diatom) and was determined as 120h-EC50 = 1337 mg/L
The ECOSAR QSAR model predicts that 30-day, NOEC cited as a ChV value would to be 178.832 mg/L (ppm) Green Algae.
The ECOSAR QSAR model predicts that 96-hr EC50 value would to be 1368.296 mg/L (ppm) for Green Algae.
The available data for saltwater algae and cyanobacteria are limited and to obtaine the value for PNECs for saltwaters is taken account a assesment factor 10 to extrapolate to EC50/NOEC following the “Guidance on Information Requirement and Chemical Safety Assessment R.10: Characterisation of dose [concentration]- response for environment”and “Table R.10-5 Assessment factors proposed for deriving PNEC water for saltwater for different data sets”, to account for the possibility that greater taxonomic diversity in the marine environment makes it likely that some marine taxa may be more sensitive than the most sensitive freshwater taxa
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 1 337 mg/L
- EC50 for marine water algae:
- 133.7 mg/L
- EC10 or NOEC for freshwater algae:
- 178.832 mg/L
- EC10 or NOEC for marine water algae:
- 17.88 mg/L
Additional information
Toxicity to aquatic algae and cyanobacteria was determined with Nitscheria linearis (diatom) and was determined as 120h-EC50 = 1337 mg/L
The ECOSAR QSAR model predicts that 30-day, NOEC cited as a ChV value would to be 178.832 mg/L (ppm) Green Algae.
The ECOSAR QSAR model predicts that 96-hr EC50 value would to be 1368.296 mg/L (ppm) for Green Algae.
The available data for saltwater algae and cyanobacteria are limited and to obtaine the value for PNECs for saltwaters is taken account a assesment factor 10 to extrapolate to EC50/NOEC following the “Guidance on Information Requirement and Chemical Safety Assessment R.10: Characterisation of dose [concentration]- response for environment”and “Table R.10-5 Assessment factors proposed for deriving PNEC water for saltwater for different data sets”, to account for the possibility that greater taxonomic diversity in the marine environment makes it likely that some marine taxa may be more sensitive than the most sensitive freshwater taxa
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