Registration Dossier
Registration Dossier
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EC number: 247-655-0 | CAS number: 26399-02-0
Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
Description of key information
No effects of the test substance on terrestrial organisms is expected
Key value for chemical safety assessment
Additional information
There are no studies available on the toxicity of 2-ethylhexyl oleate (CAS 26399-02-0) on terrestrial macroorganisms. The assessment was therefore based on a study conducted with the category member Isopropyl myristate (CAS No. 110-27-0), as part of a read across approach, which is in accordance with Regulation (EC) No. 1907/2006, Annex XI, 1.5. Grouping of substance and read across approach. Further justification is given within the endpoint summary 6.1 and within the category justification section 13. In this case of read-across, the best suited (highest degree of structural similarity, nearest physico-chemical properties) read-across substance was entered into IUCLID. Nevertheless, as can be seen in the data matrix of the category justification in Section 13, all reliable data in the category support the hazard assessment for this endpoint, by showing a consistent pattern of results.
The study conducted with Isopropyl myristate (CAS No. 110-27-0) was performed as a limit test according to OECD guideline 207 and GLP (Steber, 1999). The test organism Eisenia fetida was exposed to Isopropyl myristate in artificial soil for 14 days, at the nominal test concentration 20,000 mg/kg. No mortality occurred during the test period.
Thus, based on the above mentioned result, and due to the structural and profile similarities of the substances, as are explained with in the overall endpoint summary 6.1 it can be concluded that no toxicological effects on soil macroorganisms are expected for 2 -ethyl hexyl oleate (CAS 26399 -02 -0).
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