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EC number: 203-560-6 | CAS number: 108-20-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The substance did not exhibit toxicity to algae when tested according to method OECD 201, with 96-hour EC50 value for cell number greater than 1000 mg/L.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 1 000 mg/L
- EC10 or NOEC for freshwater algae:
- 1 000 mg/L
Additional information
Acute toxicity to Pseudokirchneriella subcapitata (previously known as Raphidocelis subcapitata and Selenastrum capricornutum) was assessed according to method OECD 201, and in compliance with OECD GLP (Stephenson, 1983). Algae were exposed to the substance at a range of concentrations with the aid of acetone as a vehicle (0.1 mL/L) in the dilution water. The toxic effect measured during the assay was the inhibition of cellular multiplication over a time period of 96 hours. The study was performed using Erlenmeyer flasks containing 50 mL of test solution inoculated with an algal suspension such that the initial cell concentration was 5x10^2 cells/mL. Test flasks were incubated at 24 ± 2 °C, continuously shaken and constantly exposed to a light intensity of about 3000 lux. The algal concentration was measured after 2 and 4 days. Physico-chemical measurements were carried out on days 0, 2, and 4 of the test. The concentration of the test substance causing a 50% reduction in cell number (EC50) was determined. None of the cultures grown in the presence of isopropyl ether had a day 4 cell count of less than 80% of the mean control cell count on day 4. The 96 hour EC50 was therefore greater than 1000 mg/L, the maximum concentration tested. The 72-hour data were not collected during the study.
Acute toxicity to aquatic algae was estimated using a validated QSAR model with the following result. The Estimation Programs Interface (EPI) Suite United States Environmental Protection Agency ECOSAR Program (v0.99h) returned the result green algae 96 hour EC50 = 134.9 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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