Registration Dossier

Toxicological information

Acute Toxicity: dermal

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Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
No data
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature

Data source

Reference
Reference Type:
secondary source
Title:
Unnamed

Materials and methods

Principles of method if other than guideline:
Insufficient details available to judge compliance with test guidelines
GLP compliance:
not specified
Test type:
other: no data

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
No data

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Type of coverage:
not specified
Vehicle:
not specified
Duration of exposure:
No data
Doses:
No data
No. of animals per sex per dose:
No data
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LDLo
Effect level:
1 500 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification
Conclusions:
In an acute dermal toxicity study (reliability score 4) the LDLo for dichloro(dimethyl)silane was 1500 mg/kg bw in rats.
Executive summary:

In an acute dermal toxicity study (reliability score 4) the LDLo for dichloro(dimethyl)silane was 1500 mg/kg bw in rats.