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EC number: 402-130-7 | CAS number: 106246-33-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1987
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Deviations:
- no
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- The source of test organism was activated sludge freshly sampled from a municipal sewage treatment plant, close to the test laboratory. The activated sludge was areated for 4 hours. 500 ml of the activated sludge was mixed with 500 ml tap-water whereafter the mixed liquor was homogenised for 5 minutes. It was then settled for 45 min. 125 ml of the supernatant was decanted to provide sufficient volume for a 1 per cent inoculum for each C02 test flask.
- Duration of test (contact time):
- 28 d
- Initial conc.:
- ca. 10 - ca. 20 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST CONDITIONS
- Solubilising agent: none, test item was sieved and added to test bottles to obtain an adequate suspension
- Test temperature: 19.2-20.5°C (climate room)
- pH: ranged from 6.9 - 7.4 in the test bottles
- pH adjusted: yes (of stock solution)
- Suspended solids concentration: 10-20 mg/L
- Continuous darkness: yes
- Composition of medium: The medium (mineral nutrient solution) contained per liter : 17 mg KH2P04, 43.6 mg K2HP04, 134.4 mg Na2HP04 x 12H20, 3.4 mg NH4Cl, 22.5 mg MgS04 x 7H20, 36.4 mg CaCl2 x 2H20, 0.6 mg FeCl3 and 40 mg (NH4)2SO4
TEST SYSTEM
- Number of culture flasks/concentration: 4 (2 per concentration)
- Method used to create aerobic conditions: mixture was aerated with CO2-free air for 24 hours
- Measuring equipment: titration
- Test performed in closed vessels: yes
- Test performed in open system: no
- Details of trap for CO2 and volatile organics if used: Ba(OH)2-solution
SAMPLING
- Sampling frequency: sampling at day 2, 5, 7, 9, 14, 19, 23, 28
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes
- Abiotic sterile control: no
- Toxicity control: no - Reference substance:
- acetic acid, sodium salt
- Preliminary study:
- No pre-test performed
- Test performance:
- P5367 was tested for its ready biodegradability in the modified Sturm test.
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 1.6
- Sampling time:
- 2 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 3.1
- Sampling time:
- 7 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 3.1
- Sampling time:
- 14 d
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 3.2
- Sampling time:
- 23 d
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 4
- Sampling time:
- 28 d
- Details on results:
- After 28 days of incubation at 19.2-20.5°C in the dark, the test substance was biodegraded for 4%. Under the same conditions sodium acetate was degraded for 61.4%. P5367 is concluded to be not biodegradable in the modified Sturm test, but due to the stringency of the test it can not be concluded that the test substance is not biodegradable under environmental conditions.
- Remarks on result:
- not measured/tested
- Results with reference substance:
- Points of degradation (reference substance):
9.3 % degradation after 2 d
25.7 % degradation after 5 d
35 % degradation after 7 d
39.6 % degradation after 9 d
49.3 % degradation after 14 d
52.3 % degradation after 19 d
60.1 % degradation after 23 d
61.4 % degradation after 28 d - Validity criteria fulfilled:
- yes
- Remarks:
- The reference substance sodium acetate was biodegraded for 61.4% and the total CO2-evolution in the blank was less than 2 mg per 3 litres medium, in conclusion the test can be regarded as valid.
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- The test item showed a biodegradation rate of 4% after 28 days and is therefore not ready biodegradable.
- Executive summary:
The biodegradability study was performed following EU-testing method C.5, as CO2-evolution test. Non adapted, freshly sampled sludge from a municipal sewage treatment plant was used and tested over a period of 28 days. Test item concentrations of 10.5 mg/l and 19.5 mg/l were used. The substance was not inhibiting the activity of the microorganisms since more carbon dioxide was generated in the presence of the substance than in its absence. The reference substance sodium acetate was biodegraded for 61.4% and the total CO2 -evolution in the blank was less than 2 mg per 3 litres medium, in conclusion the test can be regarded as valid.
Reference
Substance tested at 10.5 mg/l. At 19.5 mg/l 2.7% degradation observed. The substance was not inhibiting the activity of the microorganisms since more carbon dioxide was generated in the presence of the substance than in its absence.
Description of key information
The biodegradability study was performed following EU-testing method C.5, as CO2-evolution test. The test item showed a biodegradation rate of 4% in 28 days, whereas the reference substance sodium acetate was biodegraded for 61.4% and the total CO2 -evolution in the blank was less than 2 mg per 3 litres medium In conclusion the test can be regarded as valid.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
- Type of water:
- freshwater
Additional information
Reference: GLP-report
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