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Physical & Chemical properties

Partition coefficient

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Description of key information

The partition coefficient 1-octanol/water of isophorone diamine was determined according to OECD TG 107 (1995) and EC Method A.8 (1992) with the shake-flask method. The result was log Kow = 0.99 (Kow = 9.8) at 23 °C (pH 6.34 for water phase without test substance).

Key value for chemical safety assessment

Log Kow (Log Pow):
0.99
at the temperature of:
23 °C

Additional information

The GLP study with the shake-flask method is documented best. It characterizes the partially dissociated substance. The result from the other experimental study is in reasonable agreement. The QSAR results are somewhat higher, which reflects the fact that they characterize the undissociated substance:

log Kow = 0.79 (Hüls AG 1989,shake-flask) or 1.56 (CLOGP3) or 1.90 (Kowwin v.1.66).