Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 203-699-2 | CAS number: 109-73-9
Direct observations: clinical cases, poisoning incidents and other
Administrative data
- Endpoint:
- direct observations: clinical cases, poisoning incidents and other
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study based on scientific principles, basic data given
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 983
Materials and methods
- Study type:
- other: Expertise on odor thresholds as safeguards for toxic substances
Test guideline
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- Literature search and data evaluation based on olfactory and physico-chemical properties, comparision with TLVs if available.
- GLP compliance:
- no
Test material
- Reference substance name:
- Butylamine
- EC Number:
- 203-699-2
- EC Name:
- Butylamine
- Cas Number:
- 109-73-9
- Molecular formula:
- C4H11N
- IUPAC Name:
- butan-1-amine
- Test material form:
- liquid
- Details on test material:
- n-Butylamine [CAS No. 109-73-9], from Fluka, purity >99%
Constituent 1
Method
- Type of population:
- occupational
- Route of exposure:
- inhalation
- Reason of exposure:
- unintentional, occupational
Results and discussion
- Clinical signs:
- The mean odour threshold derived as average from three published sources (not specified) is reported to be 1.8 ppm
+- 2.5 (standard error, SE) in air and 6.2 ppm in water (average of two sources).
(Note: The high SE indicates highly variable values found in literature.)
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
