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Diss Factsheets
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EC number: 210-765-4 | CAS number: 623-03-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 106 (Adsorption - Desorption Using a Batch Equilibrium Method)
- Principles of method if other than guideline:
- In addition to the test conducted according to OECD 106 , the Koc value was estimated using PKOC v1.66.
- GLP compliance:
- not specified
- Type of method:
- other: estimation by calculation and experimental results
- Radiolabelling:
- no
- Test temperature:
- 25 °C
- Analytical monitoring:
- yes
- Type:
- Koc
- Value:
- 87
- Temp.:
- 25 °C
- Remarks on result:
- other: value determined in test according to OECD 106
- Type:
- log Koc
- Value:
- 1.94
- Temp.:
- 25 °C
- Remarks on result:
- other: value determined in test according to OECD 106
- Type:
- Koc
- Value:
- 159
- Remarks on result:
- other: Koc value as estimated using PKOC v1.66
- Type:
- log Koc
- Value:
- 2.2
- Remarks on result:
- other: log Koc value as estimated using PKOC v1.66
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- The log Koc (Koc) value of 4-chlorobenzonitrile was calculated to be 2.2 (159).
- Executive summary:
The Koc value was estimated using PKOC v1.66. The log Koc (Koc) of 4-chlorobenzonitrile was calculated to be 2.2 (159) (US EPA 2004). Experimental results (Wu et al. 2001. Estimation of the sorption of substituted aromatic compounds on the sediment of the Yangtse River. Bull Environ Contam Toxicol 66: 777 -783) show similar results: log Koc (Koc) = 1.94 (87).
Therefore, it can be concluded that 4-chlorobenzonitrile has only a low adsorption potential to soil.
Adsorption to aerosols is not expected. 4-chlorobenzonitrile has a vapour pressure of 3 Pa at 20 °C (see IUCLID section 4.6). With an average load of aerosols in the atmosphere (according to TGD, EU 2003, the specific aerosol surface is 5.6 * 10^-6 cm²/cm³), less than 0.1 % of 4-chlorobenzonitrile is adsorbed to aerosol particles.
Reference
Description of key information
The log Koc (Koc) of 4-chlorobenzonitrile was calculated to be 2.2 (159).
Key value for chemical safety assessment
- Koc at 20 °C:
- 159
Additional information
The Koc value was estimated using PKOC v1.66. The log Koc (Koc) of 4-chlorobenzonitrile was calculated to be 2.2 (159) (US EPA 2004). Experimental results (Wu et al. 2001. Estimation of the sorption of substituted aromatic compounds on the sediment of the Yangtse River. Bull Environ Contam Toxicol 66: 777 -783) show similar results: log Koc (Koc) = 1.94 (87).
Therefore, it can be concluded that 4-chlorobenzonitrile has only a low adsorption potential to soil.
Adsorption to aerosols is not expected. 4-chlorobenzonitrile has a vapour pressure of 3 Pa at 20 °C (see IUCLID section 4.6). With an average load of aerosols in the atmosphere (according to TGD, EU 2003, the specific aerosol surface is 5.6 * 10^-6 cm²/cm³), less than 0.1 % of 4-chlorobenzonitrile is adsorbed to aerosol particles.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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