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EC number: 203-091-7 | CAS number: 103-24-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
No toxic effects up to the limit of water solubility (< 0.0004 mg/L in aqua dest) for Cyprinus carpio (OECD 203)
Key value for chemical safety assessment
Additional information
Two studies investigating the short-term toxicity of Bis(2 -ethylhexyl) azelate (CAS 103-24-2) to freshwater fish are available. The static key study was conducted according to GLP and OECD guideline 203 using Cyprinus carpio as test organism (Bogers, 1998). Siphoned test solutions in concentrations of 1 to 1000 mg/L were applied. The appearance of the final test solutions ranged from clear and colourless to turbid at the higher test concentrations. A 96 h-LC50 value of > 1000 mg/L is determined on the basis of the nominal concentration. As observed undissolved test material was not removed from the treatments, adverse effects could either be caused by systemic toxicity or by physical interferences. However, as no mortality was observed in any treatment the test can be considered as appropriate to assess the hazard of the substance to fish.
A supporting study confirms the results of the key study. The study was conducted by a Japanese authority according to GLP and OECD guideline 203 using Oryzias latipes as test organism (MOE, 2004). A technical product of the substance (77.2% purity) was tested at a nominal test concentration of 0.1 mg/L using HCO-40 as vehicle. A measured test concentration of 0.0723 mg/L can be considered as highest achievable test substance concentration using a vehicle under test conditions. No mortality was observed during an exposure time of 96 h. Hence, the 96 h-LC50 is determined to be > 0.0723 mg/L (meas.) and thus above the solubility of the substance in water.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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