Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 616-391-1 | CAS number: 76812-02-7
Boiling point
Administrative data
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Study initiation: 24-09-1997 / Starting date: 24-11-1997 / End of laboratory investigation: 24-11-1997
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP study according to international guideline
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 998
- Report date:
- 1998
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- GLP compliance:
- yes
- Type of method:
- differential scanning calorimetry
Test material
- Reference substance name:
- 4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-α,α-dimethyl-ethyl ester benzeneacetic acid
- EC Number:
- 616-391-1
- Cas Number:
- 76812-02-7
- Molecular formula:
- C34 H41 N O4
- IUPAC Name:
- 4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-α,α-dimethyl-ethyl ester benzeneacetic acid
- Reference substance name:
- 4-(4-(4-Hydroxydiphenylmethyl)-1-piperidinyl)-1-oxobutyl- alpha,alphadimethylbenzeneacetic acid ethyl ester
- IUPAC Name:
- 4-(4-(4-Hydroxydiphenylmethyl)-1-piperidinyl)-1-oxobutyl- alpha,alphadimethylbenzeneacetic acid ethyl ester
- Details on test material:
- - Name of test material (as cited in study report): Fexofenadone-Ethylester
- Analytical purity: 98.65 % (w/w)
- Code-No.: HOE CG 0529 OY ZD99 0001
- Lot/batch No.: TAM 40-96-13 dated 27.08.1996
- Storage condition of test material: 2 Years in a refrigerator Exclusion of moisture. (information by the producer)
- Certificate No., date: dated 19.08.1997
- Expiration date of the certificate: August 1998
Constituent 1
Constituent 2
Results and discussion
Boiling point
- Atm. press.:
- 1 013.3 hPa
- Decomposition:
- yes
- Remarks:
- After melting of the test substance at about 120°C no endothermal effect was observed only an exothermic decomposition beginning at 160 °C.
- Decomp. temp.:
- 160 °C
Any other information on results incl. tables
The determination of the boiling point/boiling range by DSC,Mettler-ToledoTA8000, was carried out in standard aluminium pan with a hole. The precision of the procedure is approx. ± 0.5K.
After melting of the test substance at about 120°C, no endothermal effect was observed only an exothermic decomposition beginning at 160°C.
Applicant's summary and conclusion
- Conclusions:
- The melting point of the substance is 120°C.
After melting, the test substance shows an exothermal decomposition beginning at 160°C in the differential scanning calorimetry, So it is concluded that the test substance has no boiling point at atmospheric pressure.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
