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EC number: 206-532-1 | CAS number: 353-42-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriate low concentrations.
The substance may generate a shift in the pH.
Key value for chemical safety assessment
Additional information
In water, dimethyl ether - boron trifluoride rapidly decomposes to form dimethyl ether and boron trifluoride dihydrate. The latter reacts further to boric acid and fluoroboric acid, which finally hydrolyses to yield hydrofluoric acid/ fluoride ions. The assessment of toxicity to microorganisms was therefore based on studies on the substance itself as well as on boric acid, one of the final products of hydrolysis.
The acute toxicity of dimethyl ether – boron trifluoride on microorganisms was investigated, using the bacterium Pseudomonas putida as test organism. The test was conducted according to the EC Directive 79/831/EEC (C) and GLP (BASF AG, 1991). However, the pH was not adjusted and decreased to below 5 at the higher test substance concentrations (pH 2.1 at 1000 mg/L). The observed effects were therefore probably due to the low pH. Toxicity towards Scenedesmus subspicatus was also tested for the similar substance diethyl ether, with no effects observed at 100 mg/L in the neutralised sample (BASF AG, 1992).
Effects of boric acid on micro-organisms are reviewed in the EU Risk Assessment Report for boric acid. Inhibition was estimated using the standardized OECD 209 method, Hanstvelt and Schoonmade (2001) reported 24% inhibition at 175 mg-B/L, and an EC10 can be calculated from their data as 58 mg-B/L. A NOEC was reported by the study authors of 17.5 mg-B/L, but was not determined via any statistical means. In actuality, there was 4% inhibition at this exposure, so it is an EC4, thus more stringent than intended by the OECD 209 protocol. An EC10 value was calculated by linear regression from the data which showed a good fit (R2= 0.863) with a value of 58.0 mg-B/L. This study complies with GLP practice, is rated as highly reliable in quality, and is consistent with earlier tests of activated sludge, however they were not published.
Gerike et al.(1976), using an earlier version of the OECD activated sludge method reported LOEC and NOEC of 120 and 20 mg-B/L, respectively. Guhl (1992, 2000) reported activated sludge LOEC and NOEC of 50 and 20 mg-B/L, respectively.
Other reports include tests of the microbe, Pseudomonas putida, with NOEC values ranging from 7.6 to 1040 mg-B/L However, these study reports are of varying reliability and it appears that the high value (1040) is incorrect. The geometric mean value of the Henkel studies is 50.8 mg-B/L (EC10 values of 340 and 7.6 mg-B/L).
Guhl (1992, 2000) reported on ciliate growth inhibition to Entosiphon sulcatum, Opercularia bimarginata, and Paramecium caudatum, with NOEC values of 10, 15, and 20 mg-B/L, respectively. Bringmann and Kuehn (1980b) reported a toxicity threshold (EC5) to the ciliate Uronema pardaczi of 23 mg-B/L.
The data on sewage treatment plants appears consistent, specifically that no effects are seen at boron exposures of 8 to 20 mg-B/L.
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