Registration Dossier

Administrative data

Description of key information

According to the EC-standards it is concluded that MMVF fibres are not irritating to human skin and eyes.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Respiratory irritation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Additional information

Three female albino rabbits were exposed to 0.5 g of the test material under a semi-occlusive bandage for 4 hours and subsequently monitored at the intervals of 1, 24, 48, 72 hours as well as 7 and 14 days after termination of exposure. The mean score for erythema was 0 and mean score for oedema was 0. Hence the material shall not be classified as skin irritating according to Council Directive 67/548/EEC and Regulation (EC) 1272/2008. It is concluded that MMVF fibres are not irritating to human skin.

Three female albino rabbits were exposed to 0.5 g of the test material under a semi-occlusive bandage for 4 hours and subsequently monitored at the intervals of 1, 24, 48, 72 hours as well as 7 and 14 days after termination of exposure. The mean score for erythema was 0.67 and mean score for oedema was 0. Hence the material shall not be classified as skin irritating according to Council Directive 67/548/EEC and Regulation (EC) 1272/2008. It is concluded that MMVF fibres are not irritating to human skin.

Justification for classification or non-classification