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EC number: 218-871-2 | CAS number: 2269-22-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- no hazard identified
Marine water
- Hazard assessment conclusion:
- no hazard identified
STP
- Hazard assessment conclusion:
- no hazard identified
Sediment (freshwater)
- Hazard assessment conclusion:
- no hazard identified
Sediment (marine water)
- Hazard assessment conclusion:
- no hazard identified
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- no hazard identified
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential to cause toxic effects if accumulated (in higher organisms) via the food chain
Additional information
Aluminium tri sec-butylate reacts instantaneously with water to form sec-butanol and Al3+ species. The resulting pH being weakly alkaline indicates according to Langmuir et al. 2004 that Al3+ species formed are mainly Al(OH)4-, Al(OH)3 and Al(OH)2+ at pH 8.5. Thus, aluminium tri-sec-butylate is abiotically degradable and forms 2 -butanol being readily biodegradable as shown in the registration dossier of 2-butanol submitted by the same lead registrant. Hence, 2-butanol is the organic species present in aqueous media and thus the ideal surrogate for assessing toxicity to aquatic species posed by the organic moiety of the reference substance. Sec-butanol has a very low aquatic toxicity not leading to classification according to CLP (Regulation (EC) No 1272/2008) and/or DSD (Directive 67/548/EEC). Also aluminium3+ species investigated for acute aquatic toxicity did not show L(E)C50 values up to their water solubility when tested at various trophic levels. Aluminium is amongst the most common elements in the earth’s crust and can be found in great abundance in aquatic eco-systems as well as in terrestrial and sediment environments. The relative contributions of anthropogenic aluminium to the existing natural pools of aluminium in soils and sediments is therefore not relevant either in terms of added amounts or in terms of toxicity.
Conclusion on classification
Aluminium tri-sec-butylate reacts instantaneously with water to form sec-butanol and Al3+ species. The resulting pH being weakly alkaline indicates according to Langmuir et al. 2004 that Al3+ species formed are mainly Al(OH)4-, Al(OH)3 and Al(OH)2+ at pH 8.5.
As a result, aluminium tri-sec-butylate can be assessed for acute and chronic aquatic toxicity by assessing sec-butanol and hardly soluble aluminium3+ species.
Acute aquatic toxicity:
Aluminium is amongst the most common elements in the earth’s crust and can be found in great abundance in aquatic eco systems as well as in terrestrial and sediment environments. The relative contributions of anthropogenic aluminium to the existing natural pools of aluminium in soils and sediments is therefore not relevant either in terms of added amounts or in terms of toxicity. Acute tests on various trophic levels showed no acute aquatic toxicity within the limits of solubility of aluminium 3 +.
The fish, daphnia, and algae acute aquatic toxicity for sec-butanol are (48h LC50 (fish) = 3520 mg/L, 24h EC50 (daphnia) = 2300 mg/L, and 7d EyC3 (algae) > 95 mg/L).As a result, the substance does not meet the criteria for classification according to Regulation (EC) No 1272/2008, Annex I section 4.1.
Chronic aquatic toxicity: According to the Guidance on the Application of the CLP Criteria (ECHA Reference ECHA-09-G-02-EN), if the acute aquatic toxicity is greater than 100 and the substance is rapidly degradable and there is a low potential for bioaccumulation (log Kow sec-butanol = 0.65), the substance should not be classified for Chronic Aquatic Toxicity as is the case here.
In a test with eggs of the brook trout exposed to Aluminium sulphate, the lowest NOEC found for incomplete hatching was 57µg/L (as total Al at pH 6.5). For aluminium species in a long-term daphnia study no effects were found at 1.1 mg Al/L at pH 7.61. The NOEC for growth rate in fresh water species Monoraphidium dybowskii and Stichococcus sp. is is 0.04 mg/L. In salt water micro algae the EC10 for growth rate was 18µg/L. The EC50 in pseudomonas putida is 165 mg/L as Al.
The concept of biodegradation is not applicable to aluminium as being inorganic but due to the ubiquitous abundance of aluminium in the environment, anthropogenic aluminium compounds are generally not of concern.
As a result, the substance does not meet the criteria for chronic classification according to Regulation (EC) No 1272/2008, Annex I section 4.1.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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