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Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Description of key information

The 3h EC50 for toxicity of methyl ethyl sulphide to micro-organisms based on the inhibition of the respiration rate was > 1000 mg/L. This has been read across to diethyl sulphide.

Key value for chemical safety assessment

Additional information

Gancet (2012) determined the toxicity of methyl ethyl sulphide to micro-organisms according to the OECD guideline 209 “Activated Sludge, Respiration Inhibition Test”. The effect was assessed in a GLP-compliant study by measuring the micro-organisms respiration rates on a sample of activated sludge during an incubation period of 3 hours.The EC50 based on the inhibition of the respiration rate was >1000 mg/L. The study is considered reliable and suitable for use for this endpoint.

The toxicity of diethyl sulphide to micro-organisms has been read across from methyl ethyl sulphide. These substances are sulphides characterised by a sulphur atom in a carbon chain with the same structure over very similar carbon chain lengths (C4 for diethyl sulphide and C3 for methyl ethyl sulphide). Similarities between the available data for acute toxicity to Daphnia and algae show the similarity of the ecotoxicological properties of the two substances.