3'-chloropropiophenone

Endpoint summary

Additional information

Stability:

Phototransformation in air:-

The atmospheric oxidation half-life of 3’-chloropropiophenone was estimated using the level III multimedia model. The substance 3'-chloropropiophenone has got an estimated half-life of 8.8 d and hydroxyl radical reaction rate constant as 0.0000000000018 cm3/molecule-sec at 25 degrees C. Hence it can be inferred that 3'-chloropropiophenone is persistent in air medium and is not easily phototransformed in air.

Hydrolysis:-

The Hydrolysis rate constant of 3’-chloropropiophenone is estimated to be 0.0000000000034138 (3.4138 E-12) cm3/molecule-sec at half life of 37.598 h. The estimated half-life of the substance indicates that the substance is slowly hydrolysable.

Biodegradation:-

Biodegradation in water:-

The half-life period of 3'-chloropropiophenone in water is 38 d and based on this value it can concluded that the substance is not persistent in water medium since the half-life is less than the threshold of 60 days (to qualify the chemical as persistent). Also the diffusion percentage of 3'-chloropropiophenone in water medium is 22%. This coupled with the dilution of water shall result in ready biodegradability of the chemical.

Data is from PBT Profiler:

Media	Half-Life(days)	Percent in each medium
Water	38	22%

Biodegradation in water and sediment:

Half life period of 3'-chloropropiophenone in water is observed to be 38 d (912 h) while in sediment it is 340 d (8160 h).Based on these half life values of 3'-chloropropiophenone, it is concluded that the chemical is readily biodegradable in water where as it is non biodegradable in sediment. However, since there is no diffusion of the substance in the sediment as evident from the reported data (0% in sediment) and hence persistence in the sediment compartment is not likely to be critical.

Data is from PBT Profiler:

Media	Half-Life(days)	Percent in medium
Water	38	22%
Sediments	340	0

Biodegradation in soil:

The PBT Profiler & EPI Suite has estimated that 3'-chloropropiophenone is expected to be found predominantly in soil and its persistence estimate is based on its availability in this medium. Its half-life in soil, 1800 hrs (75 days). This exceeds the EPA criteria of >= 2 months (and <= 6 months). Therefore, 3'-chloropropiophenone is estimated to be persistent in the soil environment.

Data is from PBT Profiler:

Media	Half-Life(days)	Percent in each medium
Soil	75	75%

Data is from EPI Suite:

	Mass Amount (percent)	Half-Life (hr)	Emissions (kg/hr)
soil	77.5	1800	1000

Bioaccumulation:-

Bioaccumulation is the process by which the chemical concentration in an aquatic organism achieves a level that exceeds that in the water, as a result of chemical uptake through all possible routes of exposure. The relationship between bioaccumulation and bio-concentration is that, chemicals that have the potential to bioconcentrate also have the potential to bioaccumulate. Bioaccumulation is closely related to the Bioconcentration factor (BCF).

The estimated bioconcentration factor (BCF) for 3'-chloropropiophenone is 8.6 which does not exceed the bioconcentration threshold of 1000. Thus it is concluded that 3'-chloropropiophenone is not expected to bioaccumulate in the food chain because it does not exceed the BCF criteria.

Adsorption/Desorption

Soil Adsorption Coefficient i.e Koc value of 3'-chloropropiophenone was estimated as 164.6 by means of MCI method. This Koc value at 20 degree C is equivalent to 131.68.

Henry's Law constant

Henry's Law states that at a constant temperature, the amount of a given gas that dissolves in a given type and volume of liquid is directly proportional to the partial pressure of that gas in equilibrium with that liquid.

Henrys Law Constant of 3'-chloropropiophenone at 25 deg C is 0.00000459 (4.59E-006) atm m³/mol.