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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Report date:
2006

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 423 (Acute Oral toxicity - Acute Toxic Class Method)
GLP compliance:
yes (incl. QA statement)
Test type:
acute toxic class method
Limit test:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
2-(2-methoxyphenoxy)ethan-1-amine hydrochloride
EC Number:
700-259-6
Cas Number:
64464-07-9
Molecular formula:
C9H14ClNO2
IUPAC Name:
2-(2-methoxyphenoxy)ethan-1-amine hydrochloride

Test animals

Species:
rat
Strain:
Wistar
Sex:
male/female
Details on test animals or test system and environmental conditions:
Rattus norvegicus, tribe Wistar var.Alba ( albino ) laboratory rats

Administration / exposure

Route of administration:
other: oral: substance disssolved in ethanol and diluted with distilled water
Doses:
2000mg/kg dose
No. of animals per sex per dose:
3 female
3 male
Control animals:
no

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD0
Effect level:
> 2 000 mg/kg bw
Based on:
test mat.
Remarks on result:
other: LD50 not determined, no animal did not die during the test ( dose 2000mg/kg)
Mortality:
0%

Applicant's summary and conclusion

Interpretation of results:
practically nontoxic
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
According results substance is non-toxic.