Registration Dossier
Registration Dossier
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EC number: 203-374-5 | CAS number: 106-21-8
Sensitisation data (human)
Administrative data
- Endpoint:
- sensitisation data (humans)
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: report from secondary source with limited documentation, which meets basic scientific principles
Data source
Reference
- Reference Type:
- secondary source
- Title:
- Report on human maximization studies. Report to RIFM.
- Author:
- Kligman AM
- Year:
- 1 973
- Bibliographic source:
- Cited in: Opdyke, Monographs an fragrance raw materials, Food Cosmet. Toxicol., Vol. 12 (4), 535
Materials and methods
- Type of sensitisation studied:
- skin
- Study type:
- study with volunteers
Test guideline
- Qualifier:
- no guideline available
- GLP compliance:
- no
Test material
- Reference substance name:
- 3,7-dimethyloctan-1-ol
- EC Number:
- 203-374-5
- EC Name:
- 3,7-dimethyloctan-1-ol
- Cas Number:
- 106-21-8
- Molecular formula:
- C10H22O
- IUPAC Name:
- 3,7-dimethyloctan-1-ol
Constituent 1
Method
- Type of population:
- general
- Subjects:
- - Number of subjects exposed: 25
- Sex: male - Route of administration:
- dermal
- Details on study design:
- ADMINISTRATION
- Vehicle / solvent: petrolatum
- Concentrations: 8 %
Results and discussion
- Results of examinations:
- NO. OF PERSONS WITH/OUT REACTIONS COMPARED TO STUDY POPULATION
- Number of subjects with positive reactions: 0/25
- Number of subjects with negative reactions: 25/25
Summary: not sensitising
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
