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Diss Factsheets

Physical & Chemical properties

Density

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Reference
Endpoint:
relative density
Type of information:
experimental study
Adequacy of study:
key study
Study period:
7 October 2011
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study conducted in accordance with OECD and EU guidelines.
Qualifier:
according to guideline
Guideline:
EU Method A.3 (Relative Density)
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
Deviations:
no
GLP compliance:
no
Type of method:
other: gas comparison pycnometer
Type:
relative density
Density:
3.05
Temp.:
23.5 °C

Two test series with different weights were performed at ambient temperature (23.5 °C).

1st run:

Weight 5.9785 g

p1 / psi

p2 / psi

Volume / cm3

Density PPR/ g / cm3

1. measurement

19.556

12.172

1.9630

3.0456

2. measurement

19.563

12.177

1.9582

3.0531

3. measurement

19.614

12.208

1.9637

3.0444

Mean

 

 

1.9616

3.0477

 

2nd run:

Weight 7.5280 g

p1 / psi

p2 / psi

Volume / cm3

Density PPR/ g / cm3

1. measurement

19.603

12.133

2.4666

3.0520

2. measurement

19.523

12.084

2.4628

3.0566

3. measurement

19.614

12.141

2.4579

3.0628

Mean

 

 

2.4625

3.0571

 

Mean density PPR for the two test series: 3.0524 g/cm3

Relative density (compared to water at 4 °C) D4R = PPR/PW4 = 3.052g/cm3/1.000g/cm3= 3.05



Conclusions:
The relative density of bismuth subsalicylate at ambient temperature (compared to water at 4 °C) is D4R = 3.05. The ambient temperature was determined to be 23.5 °C. According to the European Commission Regulation (EC) No. 440/2008, A.3., solids can be measured at ambient temperature (20 - 25 °C).
Executive summary:

The purpose of this study was the determination of the relative density of the test item according to the European Commission Regulation (EC) No. 440/2008, Part A: Methods for the determination of physico-chemical properties. A.3. Relative Density: method: Gas comparison pycnometer and OECD test guideline, OECD 109 (1995) Density of liquids and solids and DIN 66137-2 (2004): Determination of solid state density, Part 2: Gas pycnometry.

The relative density of bismuth subsalicylate at ambient temperature (compared to water at 4 °C) is D4R = 3.05. The ambient temperature was determined to be 23.5 °C. According to the European Commission Regulation (EC) No. 440/2008, A.3., solids can be measured at ambient temperature (20 - 25 °C).

Description of key information

The relative density of bismuth subsalicylate is 3.05.

Key value for chemical safety assessment

Relative density at 20C:
3.05

Additional information

The relative density of bismuth subsalicylate at ambient temperature (compared to water at 4 °C) is D4R = 3.05. The ambient temperature was determined to be 23.5 °C. According to the European Commission Regulation (EC) No. 440/2008, A.3., solids can be measured at ambient temperature (20 - 25 °C).