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Diss Factsheets
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EC number: 461-870-9 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- no hazard identified
Marine water
- Hazard assessment conclusion:
- no hazard identified
STP
- Hazard assessment conclusion:
- no hazard identified
Sediment (freshwater)
- Hazard assessment conclusion:
- no hazard identified
Sediment (marine water)
- Hazard assessment conclusion:
- no hazard identified
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- no hazard identified
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
The majority of the data set for this substance is read across to the free acid form; however it is clear that in any biological system (and hence for the safety evaluation of human or environmental hazard assessment) there will be no difference between the qualitative effects of Reactive Yellow 201 (as a mixture of free acid, single and disodium salts) and the free acid form. In the production of both the free acid form and Reactive Yellow 201, the method of synthesis is identical up to the point of final isolation. The pH of the solution at isolation will affect which salt is produced, the dry pure product will either possess the Na or the H group on the charged oxygen. As soon as the material is dissolved again, the equilibrium will be reached almost instantly and at an acid pH the ionised form will be predominant.
No hazards were identified for the compartments freshwater and sediment, marine water and sediment, air, and soil, since there were no adverse effects on the test organisms in aquatic toxicity tests that would trigger classification. Therefore, negative impact of the substance "Reactive Yellow 201" on organisms living in the aforementioned compartments need not be expected. Due to absence of any significant bioaccumulation potential, organisms in the food chain (predators) are not at risk of secondary poisoning. For microorganisms in the STP, at the guideline compliant limit test concentration of 1000 mg/L, no respiration inhibition was measured, which is therefore the NOEC. Overall, the substance is not hazardous to the environment; PNEC values cannot be derived.
Conclusion on classification
According to the results of guideline-compliant aquatic toxicity tests on the test item there is no evidence of adverse effects to fish, invertebrates or algae up to the limit test concentration of 100 mg/L. The substance is well soluble in water and has a very low partition coefficient (< –4.35) hence there is no significant potential for bioaccumulation. Accordingly, the criteria for classification for environmental hazards as specified by Regulation (EC) No 1272/2008 are not fulfilled. The test item does not need to be classified as hazardous to the environment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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