Registration Dossier
Registration Dossier
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EC number: 235-747-3 | CAS number: 12650-88-3
Partition coefficient
Administrative data
Link to relevant study record(s)
Description of key information
log Pow is expected to be negative, but greater than -2.
Key value for chemical safety assessment
Additional information
The partition coefficient value is expected to be greater than -2, based on the fact that the logKow calculated for the lysozyme HCl salt is -2 (Livramento, 2003).
Furthermore logKow is expected to be negative, based on the results measured for enzymes; the following values supported this consideration:
- Subtilisin logPow: -3.1 [1-3]
- Amylase, lipase, cellulase logKow: -2.95 [2-3]
Reference
[1] HERA Human and environmental risk assessment on ingredients of household cleaning products - alpha-amylases, cellulases and lipases. 2005.
[2] HERA Human and environmental risk assessment on ingredients of household cleaning products - Subtilisins (Proteases). Edition 2.0. 2007.
[3] Henkel (2005) Subtilisin: log POW and solubility in water. 01.04.2005
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