Registration Dossier
Registration Dossier
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EC number: 611-631-1 | CAS number: 58190-57-1
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Key study: Based on the read-across approach from experimental data on acetone oxime (test method OECD 202, GLP study), the EC50 and NOEC (48h, based on mobility) for EAC3 in Daphnia magna were determined to be 678.73 and 520.76 mg/L respectively.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 678.73 mg/L
Additional information
Key study: Read-across approach from analogue substance acetone oxime:
An acute immobilisation test on Daphnia magna was performed on the analogue acetone oxime in accordance with OECD 202 (GLP study). 20 animals were exposed to 0 (control) 350.13, 455.17, 591.72, 769.23 and 1000 mg/L for 48h. The 48h-EC50 was determined to be 544.34 mg/L based on mobility (measured geometric mean concentration) and the 48h-NOEC was determined to be 417.65 mg/L (measured geometric mean concentration). Based on these results, the read-across approach was applied and the EC50 and NOEC (48h, based on mobility) for EAC3 in Daphnia magna were determined to be 678.73 and 520.76 mg/L respectively.
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