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EC number: 929-889-1 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.7 (Degradation: Abiotic Degradation: Hydrolysis as a Function of pH)
- GLP compliance:
- yes
- Radiolabelling:
- no
- Analytical monitoring:
- yes
- Buffers:
- - at pH value 9: borax / hydrochloric acid, Riedel de Haen Art. No. 33548, ready to use solution
- at pH value 7: potassium dihydrogen phosphate/ Di-sodium hydrogen phosphate, Riedel de Haen Art. No. 33546, ready to use solution
- at pH value 4: citric acid/ potassium hydroxide/ sodium chloride, Riedel de Haen Art. No. 33543, ready to use solution - Estimation method (if used):
- Half-time and the rate constant (first order reaction) at 25 °C were estimated according to the Arrhenius equation.
The calculation of the half times and the reaction rate constants were based on linear regression (Inc versus t and Ink versus T 1 respectively) following the first order concentration-time-law. - Details on test conditions:
- The substance was examined in each case at pH 4, 7 and 9. The test temperature was 50 °C, 65 °C and 80 °C at pH 9 and pH 7 and 50 °C at pH 4.
- Duration:
- 2 h
- pH:
- 4
- Temp.:
- 50 °C
- Initial conc. measured:
- 100 other: %
- Duration:
- 261 h
- pH:
- 7
- Temp.:
- 50 °C
- Initial conc. measured:
- 100 other: %
- Duration:
- 91 h
- pH:
- 7
- Temp.:
- 65 °C
- Initial conc. measured:
- 100 other: %
- Duration:
- 8.7 h
- pH:
- 7
- Temp.:
- 80 °C
- Initial conc. measured:
- 100 other: %
- Duration:
- 261 h
- pH:
- 9
- Temp.:
- 50 °C
- Initial conc. measured:
- 100 other: %
- Duration:
- 90.7 h
- pH:
- 9
- Temp.:
- 65 °C
- Initial conc. measured:
- 100 other: %
- Duration:
- 9.1 h
- pH:
- 9
- Temp.:
- 80 °C
- Initial conc. measured:
- 100 other: %
- Preliminary study:
- At pH value = 9 and 50 °C:
preliminary test (test 1):
The degradation reaction is given by pseudo-first order reaction (correlation coefficient 0.99752), the half-time and the rate constant ( first order reaction) is given by: t(1/2) = 311 hours, k = 2.21035E-08 /s
At pH value = 7 and 50 °C:
preliminary test (test 1):
The degradation re-action is given by pseudo-first order reaction (correlation coefficient 0.99193), the half-time and the rate constant ( first order reaction) is given by: t(1/2) = 239 hours, k = 8.05061E-07 /s
At pH value = 4 and 50 °C:
preliminary test (test 1):
The degradation reaction is given by pseudo-first order reaction (correlation coefficient 0.99979), the half-time and the rate constant ( first order reaction) is given by: t(1/2) = 1.27 hours, k= 1.51138E-04 /s - Transformation products:
- not measured
- % Recovery:
- 34.6
- pH:
- 4
- Temp.:
- 50 °C
- Duration:
- 2 h
- % Recovery:
- 44.9
- pH:
- 7
- Temp.:
- 50 °C
- Duration:
- 261 h
- % Recovery:
- 49.2
- pH:
- 7
- Temp.:
- 65 °C
- Duration:
- 91 h
- % Recovery:
- 58.9
- pH:
- 7
- Temp.:
- 80 °C
- Duration:
- 8.7 h
- % Recovery:
- 55.5
- pH:
- 9
- Temp.:
- 50 °C
- Duration:
- 261 h
- % Recovery:
- 56.2
- pH:
- 9
- Temp.:
- 65 °C
- Duration:
- 90.7 h
- % Recovery:
- 59.5
- pH:
- 9
- Temp.:
- 80 °C
- Duration:
- 9.1 h
- Key result
- pH:
- 7
- Temp.:
- 25 °C
- Hydrolysis rate constant:
- 0 s-1
- DT50:
- 6 022 h
- Type:
- (pseudo-)first order (= half-life)
- Remarks on result:
- other: calculated according to Arrhenius equation
- Key result
- pH:
- 9
- Temp.:
- 25 °C
- Hydrolysis rate constant:
- 0 s-1
- DT50:
- 8 711 h
- Type:
- (pseudo-)first order (= half-life)
- Remarks on result:
- other: calculated according to Arrhenius equation
- pH:
- 9
- Temp.:
- 50 °C
- Hydrolysis rate constant:
- 0 s-1
- DT50:
- 311 h
- Type:
- (pseudo-)first order (= half-life)
- pH:
- 9
- Temp.:
- 65 °C
- Hydrolysis rate constant:
- 0 s-1
- DT50:
- 109 h
- Type:
- (pseudo-)first order (= half-life)
- pH:
- 9
- Temp.:
- 80 °C
- Hydrolysis rate constant:
- 0 s-1
- DT50:
- 12.7 h
- Type:
- (pseudo-)first order (= half-life)
- pH:
- 7
- Temp.:
- 50 °C
- Hydrolysis rate constant:
- 0 s-1
- DT50:
- 239 h
- Type:
- (pseudo-)first order (= half-life)
- pH:
- 7
- Temp.:
- 65 °C
- Hydrolysis rate constant:
- 0 s-1
- DT50:
- 88.9 h
- Type:
- (pseudo-)first order (= half-life)
- pH:
- 7
- Temp.:
- 80 °C
- Hydrolysis rate constant:
- 0 s-1
- DT50:
- 10.9 h
- Type:
- (pseudo-)first order (= half-life)
- pH:
- 4
- Temp.:
- 50 °C
- Hydrolysis rate constant:
- 0.001 s-1
- DT50:
- 1.27 h
- Type:
- (pseudo-)first order (= half-life)
- Validity criteria fulfilled:
- yes
- Conclusions:
- The substance is degradable at pH 9, pH 7 and pH 4. The half-lives (t1/2) for the hydrolytic dissimilation calculated for 25 °C were 6022 hours for pH 7 and 8711 hours at pH9. At pH4 and 50°C a half-life of 1.27 h was determined.
- Executive summary:
The substance is degradable according to EG guideline C.7 92/69 at pH 9, pH 7 and pH 4. The calculation of the half times and the reaction rate constants were based on linear regression following the first order concentration-time-law.
The half-lives (t1/2) for the hydrolytic dissimilation calculated for 25°C were 6022 hours for pH 7 and 8711 hours for pH 9. At pH 4 and 50°C a fast degradation of the test substance was observed within a short time (1.27 hours).
Reference
Description of key information
The substance is degradable according to EG guideline C.7 92/69 at pH 9, pH 7 and pH 4. The calculation of the half times and the reaction rate constants were based on linear regression following the first order concentration-time-law.
The half-lives (t1/2) for the hydrolytic dissimilation calculated for 25°C were 6022 hours for pH 7 and 8711 hours for pH 9. At pH 4 and50°C a fast degradation of the test substance was observed within a short time (1.27 hours).
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 6 022 h
- at the temperature of:
- 25 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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