Reaction mass of potassium trifluoroacetate and potassium trifluoromethanesulphinate

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

29 Jul 2016 - 12 Oct 2016

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Version / remarks:

1995

Deviations:

yes

Remarks:

Due to a high hydrosolubility, the quantity of test item weighed was not 0.1 g as in the guideline but about 1.0 g and about 7.85 g to confirm the hydrosolubility. This was not considered to have affected the quality/interpretation of the results

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Version / remarks:

2008

GLP compliance:

yes (incl. QA statement)

Remarks:

28 Jul 2015

Type of method:

other: Preliminary test

Key result

Water solubility:

> 314 - < 334 g/L

Conc. based on:

test mat.

Temp.:

20.9 °C

pH:

3.42

Remarks on result:

completely miscible

Table 1

Assay No.	Test item weighing(g)	Volume of water added(mL)	Total volume (mL)	Solubilityobserved	Concentration (g/mL)
1	1.00151	1.0	1.4	incomplete	0.715
2		+0.2	1.6	incomplete	0.626
3		+0.2	1.8	incomplete	0.556
4		+0.2	2.0	incomplete	0.501
5		+0.5	2.5	incomplete	0.401
6		+0.5	3.0	incomplete	0.334
7		+2.0	5.0	complete	0.200
8	1.00321	+2.6	3.0	incomplete	0.334
9		+0.2	3.2	complete	0.314

Table 2

Assay No.	Test item weighing(g)	Total volume (sample + water) (mL)	Solubility observed	Concentration (g/mL)	pH value and temperature(°C)
10	7.85072	25	complete	0.314	3.40 at 21.3 °C
11	7.85060	25	complete	0.314	3.43 at 21.1 °C
12	7.85026	25	complete	0.314	3.43 at 20.3 °C

Conclusions:

The solubility in water of the test item was found to be in a range [0.314 g/mL ; 0.334 g/mL] and the mean pH value was measured at 3.42 at 20.9 °C.

Executive summary:

The objective of the study was to determine the water solubility of the test item, according to the OECD 105 guideline and EC A6 method and under GLP conditions.

The solubility in water of the test item was found to be between 314 and 334 g/L and the mean pH value was measured at 3.42 at 20.9 °C.

Description of key information

Based on the experimental data available on the dry reaction mass of potassium trifluoroacetate and potassium trifluoromethanesulphinate (as a powder form), the water solubility was found to be between 314 and 334 g/L (with a pH of 3.42 and at 20.9°C).

Key value for chemical safety assessment

Water solubility:

314 g/L

at the temperature of:

20.9 °C

Additional information

A study was conducted according to the OECD 105 guideline (and EC A6 method and under GLP conditions) to evaluate the water solubility of the Reaction mass of potassium trifluoroacetate and potassium trifluoromethanesulphinate. The solubility in water was found to be between 314 and 334 g/L at 20.9°C (with a mean pH value measured at 3.42).