6-amino-4-hydroxynaphthalene-2-sulphonic acid

Short-term toxicity to fish

Link to relevant study record(s)

Reference

Endpoint:

short-term toxicity to fish

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Data is from peer-reviewed journal

Justification for type of information:

Data is from peer-reviewed journal

Qualifier:

according to guideline

Guideline:

other: refer below

Principles of method if other than guideline:

A study was conducted to assess the toxicity effect of test material in fish in a 96 hours of exposure.

GLP compliance:

not specified

Analytical monitoring:

not specified

Vehicle:

not specified

Test organisms (species):

Leuciscus idus

Test type:

not specified

Water media type:

not specified

Total exposure duration:

96 h

Reference substance (positive control):

not specified

Duration:

96 h

Dose descriptor:

LC0

Effect conc.:

1 000 mg/L

Nominal / measured:

meas. (not specified)

Conc. based on:

test mat.

Basis for effect:

mortality (fish)

Validity criteria fulfilled:

not specified

Conclusions:

The lethal concentration (LC0) for the test substance, in fish Leuciscus idus on a mortality effect was observed to be 1000 mg/L.

Executive summary:

A study was conducted to assess the toxicity effect of test material on fish Leuciscus idus for a 96 hours of exposure. The 0% mortality i.e. LC0 was observed to be 1000 mg/L. Thus, it is concluded that the test substance does not exhibit toxicity to fish and can be considered to be not classified as per CLP criteria.

Description of key information

Short term toxicity to fish:

A study was conducted to assess the toxicity effect of test material on fish Leuciscus idus for a 96 hours of exposure. The 0% mortality i.e. LC0 was observed to be 1000 mg/L. Thus, it is concluded that the test substance does not exhibit toxicity to fish and can be considered to be not classified as per CLP criteria.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish

Effect concentration:

1 000 mg/L

Additional information

Short term toxicity to fish:

Available data from peer reviewed journals were described to conclude the Short term toxicity of tes material to fish as follows.

A study was conducted to assess the toxicity effect of test material on fish Leuciscus idus for a 96 hours of exposure. The 0% mortality i.e. LC0 was observed to be 1000 mg/L. Thus, it is concluded that the test substance does not exhibit toxicity to fish and can be considered to be not classified as per CLP criteria.

In another peer reviewed journal test was conducted on Rainbow trout , Bluegill sunfish and Sea lamprey larvaes.

Bluegill sunfish:

Observation on the toxic effect test material on rainbow trout (Salmo gairdneri) was evalutaed for 24 h.Fishes were obtained from the stocks of local state and Fedral fish hatcheries and were held in large raceways.6 fishes per concentration were placed together in a 10-liter glass battery containing 5 liters of water. These jars were provided with aeration through standard stone air – breakers. 12 such replicates were observed.

 Observations of each test were made approximately six times, at various intervals, during the 24-hour test period.No adverse effects were observed after 24 h when treated at concentration 5.0 mg/l.

Rainbow trout:

Observation on the toxic effect test material on rainbow trout (Salmo gairdneri) was evalutaed for 24 h.Fishes were obtained from the stocks of local state and Fedral fish hatcheries and were held in large raceways.6 fishes per concentration were placed together in a 10-liter glass battery containing 5 liters of water. These jars were provided with aeration through standard stone air – breakers. 12 such replicates were observed.

 Observations of each test were made approximately six times, at various intervals, during the 24-hour test period.No adverse effects were observed after 24 h when treated at concentration 5.0 mg/l.

Sea lamprey larvaes:

Observation on the toxic effect test material on (Petromyzon marinus) larvae was evalutaed for 24 h.Larval lampreys were collected by means of an electric shocker in the Ocqueoc River , Presque Isle County, Michigan, and were held in running water in aquaria and small "races" under conditions which stimulated there natural stream habitat.6 larvas per concentration were placed together in a 10-liter glass battery containing 5 liters of water. These jars were provided with aeration through standard stone air – breakers. 12 such replicates were observed.

 Observations of each test were made approximately six times, at various intervals, during the 24-hour test period.No adverse effects were observed after 24 h when treated at concentration 5.0 mg/l.

Thus, it is concluded that the test substance does not exhibit toxicity to fish and can be considered to be not classified as per CLP criteria.