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Diss Factsheets
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EC number: 259-653-7 | CAS number: 55466-76-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- not specified
- GLP compliance:
- yes (incl. QA statement)
- Analytical monitoring:
- yes
- Details on sampling:
- Water samples taken at 0 and 48 hours for analysis
- Vehicle:
- no
- Details on test solutions:
- Preliminary range-finding study conducted at 0.010, 0.10, 1.0, 10 and 100mg/l.
In the definitive study, test material dissolved directly in water and ultrasonicated for 30 minutes, before being diluted to a 100 mg/L test concentration. - Test organisms (species):
- Daphnia magna
- Details on test organisms:
- 1st instar Dapnia magna from in-house laboratory cultures. Fed daily with a suspension of algae.
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
- Post exposure observation period:
- No data
- Test temperature:
- 21°C
- pH:
- 6.9-8.2
- Dissolved oxygen:
- 8.1-8.4
- Salinity:
- Not applicable
- Nominal and measured concentrations:
- Limit test at a nominal concentration of 100mg/L. Measured concentrations close to nominal therefore EC50 value reported based on nominal concentrations.
- Details on test conditions:
- Test vessel: 250ml glass jars used and covered to reduce evaporation
Aeration: Test vessels were not aerated.
No of organisms per vessel: 10 daphnids per vessel
No of replicates per concentration: Four replicate test vessels prepared with duplicate control vessels
Photoperiod: 16h light: 8h dark
Feeding: No feeding during the exposure. - Reference substance (positive control):
- not specified
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Duration:
- 48 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Details on results:
- No immobilisation in the 40 daphnids exposed.
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The 48-hour EC50 for ruthenium acetate to Daphnia magna was determined to be >100 mg/L.
- Executive summary:
This is a GLP compliant study following OECD guideline 202 and is considered suitable for use as the key study for this endpoint. Based on results from a preliminary test a limit test at 100 mg/L was conducted for the definitive study. Test concentrations were analysed and were close to nominal, therefore the EC50 value was reported based on nominal concentrations. The 48-hour EC50 for ruthenium acetate to Daphnia magna was determined to be >100 mg/L.
Reference
Description of key information
The 48-hour EC50 for ruthenium acetate to Daphnia magna was determined to be >100 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 100 mg/L
Additional information
Wetton and Mulle (2001) is a GLP compliant study following OECD guideline 202 and is considered suitable for use as the key study for this endpoint. Based on results from a preliminary test a limit test at 100 mg/L was conducted for the definitive study. Test concentrations were analysed and were close to nominal, therefore the EC50 value was reported based on nominal concentrations. The 48-hour EC50 for ruthenium acetate to Daphnia magna was determined to be >100 mg/L.
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