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Diss Factsheets
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EC number: 944-090-8 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
An assessment of the hydrolysis of Reaction mass of morpholine and 6-[(p-tosyl)amino]hexanoic acid, compound with morpholine (1:1) was performed based on the behaviour of the individual constituents of the substance. The assessment concluded that is likely that the substance will be stable to hydrolysis under pH and temperature conditions of physiological and environmental relevance.
An expert assessment of the adsorption/desorption potential of Reaction mass of morpholine and 6-[(p-tosyl)amino]hexanoic acid, compound with morpholine (1:1) was performed based on the physico-chemical properties of the constituents of the substance. A substance is regarded as having the potential for adsorption if it has a Log Koc or Log Kow ≥3. The organic constituents of Reaction mass of morpholine and 6-[(p-tosyl)amino]hexanoic acid, compound with morpholine (1:1), in their ionised and un-ionised forms have Log Koc and/or Log Kow values that are below the adsorption trigger value of 3. The substance is expected to have a low potential for adsorption and, therefore, additional adsorption-desorption data is not required under REACH Annex VIII. Any sorption of Reaction mass of morpholine and 6-[(p-tosyl)amino]hexanoic acid, compound with morpholine (1:1)] to soil or sediment is expected to be negligible.
The ready biodegradation of the test substance was determined in a biological oxygen demand (BOD), GLP-certified test undertaken in accordance with OECD Guideline 306 (Biodegradability in Seawater).
The aim of the OECD 306 test is to establish the biodegradability of an organic material in a marine environment. Natural seawater considered to be biologically active was acquired from North Wales and nutrient fortified for use as the study inoculum. The registration substance at 2.5 and 3.0 mg/l, sodium benzoate at 2.5 mg/l (as a reference material to monitor microbial activity), and a seawater only blank were maintained at 17.5 - 20.5°C in the dark and reviewed on day 0, 3, 7, 14, 21, and 28. Measurement for oxygen was taken in the form of DOC at the time intervals specified and COD calculated. DOC and COD were used to determine percentage (%) biodegradability of the test material. The % biodegradation of sodium benzoate was reported to be 71.9 % over the 28-day study duration, indicating a biologically active inoculum, with a DOC of 3.83 mgO2/L. COD for the test substance was found to be 1.571 mg/mg. By the end of the experiment on Day 28, the test substance at 2.5 and 3.0 mg/l had been biodegraded by 26.2 and 19.5% (5.81 and 5.87 mgO2/L), respectively. It can be concluded that the substance is not ready biodegradable.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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