Registration Dossier
Registration Dossier
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EC number: 807-448-3 | CAS number: -
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Data waiving:
- study technically not feasible
- Justification for data waiving:
- the study does not need to be conducted because the substance is highly insoluble in water
Reference
Description of key information
The test item is expected to have a low potential for hydrolysis due to the fact that it is essentially insoluble in water.
Key value for chemical safety assessment
Additional information
The test item is a complex mixture for which the test guidelines for hydrolysis are not recommended. This is not only because components could have differenct hydrolytic rates but also hydrolysis products can be analytically indistinguishable from the starting components.
The test item as a whole was expected to be essentially insoluble in water (water solubility reported as < 0.13 mg/L). Therefore, the test solution concentration required that would dissolve all the components would be impractically low in order to perform the test and a sufficiently sensitive analytical method was not available. Overall, these issues would make hydrolysis testing unfeasible.
The main functional groups in the components of the test item which have the potential to hydrolyze are esters. Although esters usually hydrolyze readily, especially in alkaline conditions, some components of the test item may have a reduced hydrolytic potential due to them being essentially insoluble in water.
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