Registration Dossier
Registration Dossier
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EC number: 937-130-0 | CAS number: -
Hydrolysis
Administrative data
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- February 24th 2011 to June 20th 2011
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 011
- Report date:
- 2011
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 111 (Hydrolysis as a Function of pH)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- Certificate n°: GIPC 2011/13 March 7th 2011
Test material
- Reference substance name:
- Epoxy Resin T1600
- EC Number:
- 937-130-0
- IUPAC Name:
- Epoxy Resin T1600
Constituent 1
- Radiolabelling:
- no
Study design
- Analytical monitoring:
- yes
Duration of testopen allclose all
- Duration:
- 5 d
- pH:
- 1.2
- Temp.:
- 50 °C
- Initial conc. measured:
- 8.3 mg/L
- Duration:
- 5 d
- pH:
- 4.5
- Temp.:
- 50 °C
- Initial conc. measured:
- 10.8 mg/L
- Duration:
- 5 d
- pH:
- 7
- Temp.:
- 50 °C
- Initial conc. measured:
- 8.5 mg/L
- Duration:
- 5 d
- pH:
- 9
- Temp.:
- 50 °C
- Initial conc. measured:
- 12.8 mg/L
Results and discussion
- Transformation products:
- yes
Identity of transformation products
- No.:
- #1
Reference
- Reference substance name:
- Unnamed
- IUPAC name:
- Dissolved organic carbon
- Identifier:
- common name
- Identity:
- Dissolved organic carbon
Total recovery of test substance (in %)open allclose all
- % Recovery:
- 4.92
- St. dev.:
- 19.2
- pH:
- 1.2
- Temp.:
- 50 °C
- Duration:
- 5 d
- % Recovery:
- 8.14
- St. dev.:
- 31.8
- pH:
- 4.5
- Temp.:
- 50 °C
- Duration:
- 5 d
- % Recovery:
- 9.04
- St. dev.:
- 35.3
- pH:
- 7
- Temp.:
- 50 °C
- Duration:
- 5 d
- % Recovery:
- 3.23
- St. dev.:
- 12.6
- pH:
- 9
- Temp.:
- 50 °C
- Duration:
- 5 d
Any other information on results incl. tables
The hydrolysis as a function of pH of the test item Epoxy Resin T1600 was assessed according to the OECD guideline 111.
The objective of the study was to determine the rate of hydrolysis of the test item in different buffers and at different temperatures.
The preliminary test showed that the item was stable at pH 1.2,4.5, 7 and 9 at 50°C. After 5 days, less than 10% of hydrolisis were observed through analysis of dissolved organic carbon.
As specified in the OECD guideline 111, EPOXY RESIN T1600 is considered as hydrolytically stable and no additionnal testing is required.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- As specified in the OECD guideline 111, EPOXY RESIN T1600 is considered as hydrolytically stable and no additionnal testing is required.
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