Barium europium strontium silicate

Water solubility

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2011-08-08 to 2011-08-24

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

GLP compliance:

no

Type of method:

flask method

Key result

Water solubility:

528 mg/L

Temp.:

20 °C

pH:

12.2

Remarks on result:

other: Concentration of Barium ion; relative standard deviation 9.2%

Key result

Water solubility:

488 mg/L

Temp.:

20 °C

pH:

12.2

Remarks on result:

other: Concentration of Strontium ion; relative standard deviation 9.3%

Key result

Water solubility:

< 0.05 mg/L

Temp.:

20 °C

pH:

12.2

Remarks on result:

other: The concentration of Europium ion is below the detection limit

Details on results:

Because it is known that the test substance is hardly soluble in water, no preliminary test was conducted. According to the guideline for low solubility chemicals the column elution method should be applied. Due to the very low solubility of the test item in organic solvents, this test could not be performed. Instead the flask solubility test was conducted.
Due to the known low water solubility of the test substance concentration determination for the complete test item was not possible.
In the flask test solubility concentrations for the cationic residues (barium, strontium, europium) were measured by ICP OES from the water extracts of the test item. For each test, the concentration of a blank item was measured. The resulting value for the blank items were smaller than 0.05 mg/L which corresponds to the detection limit.

Conclusions:

Due to low solubility concentration of test item could not be determined. Instead solubilities of the cationic ingredients were determined.
The cationic ingredients (barium and strontium) of the test item are moderately soluble. The europium cationic residue is insoluble.

Reference 2

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

supporting study

Study period:

2011-08-22 to 2011-09-01

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

GLP compliance:

no

Type of method:

flask method

Key result

Water solubility:

287 mg/L

Temp.:

20 °C

pH:

12.1

Remarks on result:

other: Concentration of Barium ions; relative standard deviation 0.5%

Key result

Water solubility:

524 mg/L

Temp.:

20 °C

pH:

12.1

Remarks on result:

other: Concentration of Strontium ions; relative standard deviation 0.1%

Key result

Water solubility:

< 0.05 mg/L

Temp.:

23 °C

pH:

12.1

Remarks on result:

other: Concentration of Europium ions below the detection limit

Details on results:

Because it is known that the test substance is hardly soluble in water, no preliminary test was conducted. According to the guideline for low solubility chemicals the column elution method should be applied. Due to the very low solubility of the test item in organic solvents, this test could not be performed. Instead the flask solubility test was conducted measuring concentrations of the cationic residues (barium, strontium, europium) from the water extracts by ICP OES. Furthermore concentration of blank items were measured. Measured values for the blank concentrations were < 0.05 mg/L which is the detection limit.

Conclusions:

Due to low solubility concentration of test item could not be determined, the cationic ingredients (barium and strontium) are moderately soluble. The europium ionic residue is insoluble.

Reference 3

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

supporting study

Study period:

2011-04-27 to 2011-05-17

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

GLP compliance:

no

Type of method:

flask method

Key result

Water solubility:

< 0.05 mg/L

Temp.:

20 °C

pH:

12.1

Remarks on result:

other: Concentration of Barium ion

Key result

Water solubility:

< 0.05 mg/L

Temp.:

20 °C

pH:

12.1

Remarks on result:

other: Concentration of Strontium ion

Key result

Water solubility:

< 0.05 mg/L

Temp.:

20 °C

pH:

12.1

Remarks on result:

other: Concentration of Europium ions

Details on results:

In a preliminary test 3,5 mg of the test substance were put into 500ml of water by roomtemperature and stirred for 24 hours. The test substance did not dissolve (visual examination), but it changed its colour from yellow to white. According to the guideline for low solubility chemicals the column elution method should be applied. Due to the very low solubility of the test item in organic solvents, this test could not be performed. Instead the flask test solubility could be conducted measuring concentrations of the cationic residues (barium, strontium, europium) from the water extracts by ICP OES. Due to the low solubility of the test substance in the flask test, its concentrations were not measured. Furthermore concentration of blank items were measured. Determined concentrations of the blank items were < 0.05 mg/L which is the detection limit.

Conclusions:

Due to low solubility concentration of test item could not be determined. The cationic ingredients (barium, europium, and strontium ions) of the test items do not dissolve.

Reference 4

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

supporting study

Study period:

2011-08-08 to 2011-08-24

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

GLP compliance:

no

Type of method:

flask method

Key result

Water solubility:

829 mg/L

Temp.:

20 °C

pH:

12.2

Remarks on result:

other: Concentration of Barium ions; relative standard deviation: 5.6%

Key result

Water solubility:

411 mg/L

Temp.:

20 °C

pH:

12.1

Remarks on result:

other: Concentration of Strontium ions; relative standard deviation: 5.1%

Key result

Water solubility:

< 0.05 mg/L

Temp.:

20 °C

pH:

12.1

Remarks on result:

other: Concentration of Europium ions below the detection limit

Details on results:

Because it is known that the test substance is hardly soluble in water, no preliminary test was conducted. According to the guideline for low solubility chemicals the column elution method should be applied. Due to the very low solubility of the test item in organic solvents, this test could not be performed. Instead the flask solubility test was conducted.
Due to low solubility of the test item concentration measurements were restricted to cationic residues (barium, calcium, strontium, europium).
The concentrations from the water extracts were measured by ICP OES. For each test, the concentration of a blank item was measured. The resulting concentration values for the blank items (< 5*10^-2 mg/L) were below the detection limit

Conclusions:

Due to low solubility concentration of test item could not be determined, the cationic ingredients (barium and strontium) are moderately soluble. The europium ionic residues are insoluble.

Reference 5

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

supporting study

Study period:

2011-08-22 to 2011-09-01

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Remarks:

Relative standard deviation for measuring calcium ion concentration is 36,3% and higher than the maximum accepted value of 15% for high soluble compounds (solubility of high soluble compounds normally determined by flask-method) or 30% for low soluble compounds (normally determined by column-elution methods). The variations are nearly in the same range of low soluble compounds. Measured concentration value is about 0.1 mg/L.

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

GLP compliance:

no

Type of method:

flask method

Key result

Water solubility:

0.38 g/L

Temp.:

20 °C

pH:

12

Remarks on result:

other: Concentration of Barium ion; relative standard deviation: 9.8%

Key result

Water solubility:

0.47 g/L

Temp.:

20 °C

pH:

12

Remarks on result:

other: Concentration of Strontium ion; relative standard deviation: 11.1%

Key result

Water solubility:

< 0.05 mg/L

Temp.:

20 °C

pH:

12

Remarks on result:

other: Concentration of Europium ions

Key result

Water solubility:

0.12 mg/L

Temp.:

20 °C

pH:

12

Remarks on result:

other: Concentration of Calcium ion; relative standard deviation 36.3%

Details on results:

Because it is known that the test substance is hardly soluble in water, no preliminary test was conducted. According to the guideline for low solubility chemicals the column elution method should be applied. Due to the very low solubility of the test item in organic solvents, this test could not be performed. Instead the flask solubility test was conducted. Due to low solubility of the test item measurements were restricted to cationic residues (barium, calcium, strontium, europium). Concentrations were determined by ICP OES. Furthermore concentration of blank items were measured. Measured values for the blank concentrations were < 0.05 mg/L which is the detection limit.

Conclusions:

Due to low solubility concentration of test item could not be determined. The cationic residue europium is insoluble, the cationic residue calcium has very small solubility (0.12 mg/L +/- 36.3%) whereas the cationic residues strontium (solubility 0.47 g/L) and barium (solubility 0.38 g/L) are moderately soluble.

Description of key information

The test item has low solubility. Cationic ingredients like barium and strontium dissolve in water.They are moderately soluble. The cationic ingredient europium is not soluble in water. This result is confirmed by the supporting studies showing low to moderate solubility of cationic ingredients. Again, europium does not dissolve in water.