Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 429-990-6 | CAS number: -
Endpoint summary
Administrative data
Link to relevant study record(s)
- Endpoint:
- basic toxicokinetics in vitro / ex vivo
- Adequacy of study:
- key study
- Objective of study:
- other: Assessment of toxicokinetic behaviour
- Conclusions:
- In conclusion, no bioaccumulation potential based on study results is concluded.
Reference
Description of key information
Key value for chemical safety assessment
- Bioaccumulation potential:
- no bioaccumulation potential
Additional information
Effects following repeat oral exposure confirm that absorption takes place and adaptive changes indicated by effects on enzymes would suggest that a certain level of metabolism is taking place. The substance quickly loses its identity in water and it is probable that exposure to animals is to the breakdown products. The breakdown products are water soluble and are thought unlikely to accumulate. Changes in the kidney in the repeat dose study indicate that the substance or its metabolites passes through the kidney, but there is no evidence as to whether renal excretion takes place.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
