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Diss Factsheets

Physical & Chemical properties

Solubility in organic solvents / fat solubility

Administrative data

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
2009
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: only visual testing for the estimation of solubility

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2009
Report date:
2009

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Visual testing of the solubility after shaking the test substance in the solvent at room temperature
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
N-[4-(aminocarbonyl)phenyl]-4-nitrobenzamide
EC Number:
298-791-2
EC Name:
N-[4-(aminocarbonyl)phenyl]-4-nitrobenzamide
Cas Number:
93839-21-5
Molecular formula:
C14H11N3O4
IUPAC Name:
N-(4-carbamoylphenyl)-4-nitrobenzamide
Details on test material:
Purity: 98.01 %

Results and discussion

Solubility in organic solvents / fat solubilityopen allclose all
Medium:
DMSO
Solubility:
> 1 g/L
Temp.:
22 °C
Remarks on result:
other: visual estimation
Medium:
n-octanol
Solubility:
< 1 mg/L
Temp.:
22 °C
Remarks on result:
other: visual estimation
Test substance stable:
yes

Applicant's summary and conclusion

Conclusions:
The estimated solubility at 22°C of the test item is
> 1 g/L in DMSO
< 1 mg/L in n-octanol