Registration Dossier
Registration Dossier
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EC number: 279-348-2 | CAS number: 79915-74-5
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
In a standard ready biodegradability test according to OECD 301C, the substance was found to be readily biodegradable at a test concentration of 100.6 mg/L. This value is considered as NOEC.
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 100.6 mg/L
Additional information
Absence of microbial toxicity can often be inferred from biodegradation studies in the laboratory. The information content of ready biodegradability tests can under certain conditions also be used to derive a NOEC in order to avoid new testing (ECHA R.7b, v3.0 (Feb. 2016)). A ready biodegradability test relying on continuous monitoring is considered more reliable for observing the effects of a chemical on the inoculum. A GLP study, following the MITI protocol has concluded on the ready biodegradability of Sakura Salicylate. As the actual NOEC for STP microorganisms is probably higher, use of the value of 100.6 mg/ L is considered to be a conservative approach for chemical safety assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
