2,2-dimethyl-1,3-propanediyl didecanoate

Ecotoxicological Summary

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:

no hazard identified

Marine water

Hazard assessment conclusion:

no hazard identified

STP

Hazard assessment conclusion:

no hazard identified

Sediment (freshwater)

Hazard assessment conclusion:

no hazard identified

Sediment (marine water)

Hazard assessment conclusion:

no hazard identified

Hazard for air

Air

Hazard assessment conclusion:

no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:

no hazard identified

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:

insufficient hazard data available (further information necessary)

Conclusion on classification

According to Article 13 of Regulation (EC) No 1907/2006 "General Requirements for Generation of Information on Intrinsic Properties of substances", information on intrinsic properties of substances may be generated by means other than tests e.g. from information from structurally related substances (grouping or read-across), provided that conditions set out in Annex XI are met. Annex XI, "General rules for adaptation of this standard testing regime set out in Annexes VII to X” states that “substances whose physicochemical, toxicological and ecotoxicological properties are likely to be similar or follow a regular pattern as a result of structural similarity may be considered as a group, or ‘category’ of substances. This avoids the need to test every substance for every endpoint”.

A read-across approach was applied to Neopentyl glycol dicaprate (CAS No. 27841-06-1) for ready biodegradability and aquatic toxicity. Once the read-across approach is applied, substances will be classified and labelled on this basis.

 

Environmental fate and pathways

Degradation

Biodegradation: readily biodegradable,≥90.2% after 28 d (OECD 301B); read-across

Bioaccumulation

No potential for bioaccumulation

Aquatic acute toxicity

Fish, LC50 (96 h) > 0.086 mg/L (measured, geometric mean;Oncorhynchus mykiss); no effects up to the limit of water solubility; read-across CAS 68855-18-5

Fish, LL50 (96 h) > 100 mg/L (nominal;Oncorhynchus mykiss); no effects up to the limit of water solubility; read-across CAS 85186-86-3

Aquatic invertebrates, EL50 (48h) > 100 mg/L (nominal;Daphnia magna); no effects up to the limit of water solubility; read-across CAS 85186-86-3

Algae, EL50 (72 h) > 0.0065 mg/L (measured, geometric mean;Pseudokirchneriella subcapitata); no effects up to the limit of water solubility; read-across CAS 68855-18-5

Algae, EL50 (72 h) > 100 mg/L (nominal;Desmodesmus subspicatus); no effects up to the limit of water solubility; read-across CAS 85186-86-3

Aquatic chronic toxicity

Fish: no data available

Aquatic invertebrates, NOEC (21 d)≥0.0019 mg/L (measured, TWA;Daphnia magna); no effects up to the limit of water solubility; read-across CAS 68855-18-5

Algae, NOELR (72 h)≥0.0065 mg/L (measured, geometric mean;Pseudokirchneriella subcapitata); no effects up to the limit of water solubility; read-across CAS 68855-18-5

Algae, EL0 (72 h)≥100 mg/L (nominal;Desmodesmus subspicatus); no effects up to the limit of water solubility; read-across CAS 85186-86-3

CLP

Based on the data above, the substance is predicted to be readily biodegradable, and neither short-term nor long-term toxic effects towards aquatic organisms of all three trophic levels are expected up to the limit of the water solubility (< 2.4 µg/L). Therefore, Neopentyl glycol dicaprate (CAS No. 27841-06-1) does not need to be classified and labelled as environmentally hazardous, according to the consolidated version of Regulation (EC) No 1272/2008 and further amendments (ATPs).