Registration Dossier
Registration Dossier
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EC number: 247-655-0 | CAS number: 26399-02-0
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
No toxic effects on microorganisms were observed at the highest test concentration
Key value for chemical safety assessment
Additional information
No studies on toxicity to microorganisms are available for 2-ethylhexyl oleate (CAS 26399-02-0). The assessment was therefore based on a study conducted with the category member Fatty acids, C16-18 and C18-unsatd., 2-ethylhexyl esters (CAS 85049-37-2), as part of a read across approach, which is in accordance with Regulation (EC) No. 1907/2006, Annex XI, 1.5. Grouping of substance and read across approach. Further justification is given within the endpoint summary 6.1 and within the category justification section 13. In this case of read-across, the best suited (highest degree of structural similarity, nearest physico-chemical properties) read-across substance was entered into IUCLID. Nevertheless, as can be seen in the data matrix of the category justification in Section 13, all reliable data in the category support the hazard assessment for this endpoint, by showing a consistent pattern of results.
In the selected key study conducted with Fatty acids, C16-18 and C18-unsatd., 2-ethylhexyl esters (CAS 85049-37-2), the acute toxicity to activated sludge was tested according to OECD 209 under GLP conditions (Van der Kerken 1995). After an incubation time of 3 hours, there was no inhibition of the respiration rate observed within the tested concentration range of 6.5 to 100.2 mg/L (nominal), resulting in an EC50(3h) value of >100 mg/L.
Thus, based on the above mentioned result, and due to the structural and profile similarities of the substances, as are explained with in the overall endpoint summary 6.1 it can be concluded that no toxicological effects on microorganisms are expected for 2 -ethylhexyl oleate (CAS 26399 -02 -0).
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